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New Vaccines and Chemotherapy
Viral Vaccines Joseph L. Melnick As with history in general, the history of vaccines needs to be reexamined and updated. My task is to look back to see what has been successful and to look forward to see what remains to be accomplished in the prevention of viral diseases by vaccines. Also, I shall refer to the pertinent material discussed at two recent conferences of the Institute of Medicine, National Academy of Sciences, on virus vaccines under development and their target populations in the United States (1985b) and in developing countries (1986). These reports, plus a third on Vaccine Supply and Innovation (1985a), should be required reading for all those in both the public and the priva...
Applied Virology Research
Volume 3 is devoted to the latest diagnostic technology for virus diseases, particularly molecular methodologies.
Virus Variability, Epidemiology and Control
Virus Variability and Impact on Epidemiology and Control of Diseases E. Kurstak and A. Hossain I. INTRODUCTION An important number of virus infections and their epidemic developments demonstrate that ineffec tiveness of prevention measures is often due to the mutation rate and variability of viruses (Kurstak et al., 1984, 1987). The new human immunodeficiency retroviruses and old influenza viruses are only one among several examples of virus variation that prevent, or make very difficult. the production of reliable vaccines. It could be stated that the most important factor limiting the effectiveness of vaccines against virus infections is apparently virus variation. Not much is, how ever, k...
Applied Virology
Applied Virology covers the practical applications of the developments in basic virology, not only to virology but to other disciplines as well, and demonstrates the impact of virus diseases on the environment, economy, and the health of man, animals, and plants. The book discusses topics on new virus vaccine technology and chemotherapy; the status of vaccination against viral diseases; and the epidemiology and diagnosis of viral diseases. The text provides information on the strategy used to produce virus vaccines; on antiviral chemical compounds; on simple, rapid, and specific diagnostic techniques; and on epidemiology in relation to the prevention and control of virus diseases. Noninfectious, synthetized peptides used as safe virus vaccines are reviewed with special attention to their immunogenicity, multispecificity, and usefulness in case of epidemics. Virologists will find the book useful.
Enzyme Immunodiagnosis
Enzyme Immunodiagnosis focuses on the applications of enzyme immunodiagnosis procedures to the detection of drugs, infectious disease pathogens, and antigens in cancer pathology. This book discusses the use of immunoassays in vaccine assessment and standardization, including the application of commercial enzyme immunoassays (EIA) kits, automation of assays, and interpretation of results obtained with both serological and immunohistochemical methods. The developments in immunoblotting applications to diagnosis and research and use of polyclonal or monoclonal antibodies in enzyme immunodiagnosis are also reviewed. This book is beneficial to students and specialists conducting work on immunoenzymatic technology, as well as those involved in research, development, teaching, and diagnosis in fields in immunoassays.
Advances in Virus Research
The Advances in Virus Research series covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. This eclectic volume contains six reviews covering topics relating to plant viruses, evolution of viruses with hosts and cell recognition by viruses. Six Comprehensive Reviews on: * Varicella Virus - Mononuclear Cell Interaction * Evolution of Cell Recognition by Viruses: A Source of Biological Novelty with Medical Implications * Infectious Pancreatic Necrosis Virus: Biology, Pathogenesis and Diagnostic Methods * Structures of Picrona-like plant viruses: Implications and Applications * Cucumoviruses * Co-Evolution of Viruses with Hosts and Vectors and Possible Paleontology
Methods in Muscle Biology
Methods in Muscle Biology is a comprehensive laboratory guide that details the methods used in the study of muscle biology. The techniques included embrace cell, developmental, and molecular biology, as well asphysiology, neurobiology, and medical research.
Foot and Mouth Disease
The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptabl
