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This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Cl...
Vascular injury is initiated by oxidant injury to the vessel wall. This volume is organized around the role of oxidant damage in this disease process and provides a collection of the most recent studies, representing various disciplines that can serve as the basis for further improvements in our understanding and control of cardiovascular and cerebral vascular disease.
This book constitutes the refereed proceedings of the 24th Conference on Medical Image Understanding and Analysis, MIUA 2020, held in July 2020. Due to COVID-19 pandemic the conference was held virtually. The 29 full papers and 5 short papers presented were carefully reviewed and selected from 70 submissions. They were organized according to following topical sections: image segmentation; image registration, reconstruction and enhancement; radiomics, predictive models, and quantitative imaging biomarkers; ocular imaging analysis; biomedical simulation and modelling.
Clinical Cardio-oncology is a comprehensive, clinically focused title for cardiologists, oncologists, and specialists in cardio-oncology programs who need up-to-date knowledge about the cardiovascular effects of cancer treatment, especially on long-term cancer survivors. This brand-new resource covers the implementation of cardio-oncology into your practice, while a strong focus on patient management offers helpful information on coordinating care before, during, and after therapy. Its highly organized four-section format allows readers to quickly and easily locate relevant information. - Comprised of four sections for quick and easy reference: Oncology and Hematology Principles; Cardiac Com...
Aldosterone, Volume 109, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to Aldosterone Research, Aldosterone and Micrornas, the Evolution of the Mineralocorticoid Receptor, Aldosterone and Kidney Micrornas, Adipocyte Mineralocorticoid Receptor, Regulation of Aldosterone Secretion, Leptin and Aldosterone, Cell- and Ligand-Specific Interactions in Mineralocorticoid Receptor Signaling, Primary Aldosteronism, Present and Future, Aldosterone-Producing Adenomas, Overexpression of the Mineralocorticoid Receptor, Aldosterone and Myocardial Pathology, and much more.
Today's patients have unique cardiologic needs before, during, and after cancer treatment. Chemotherapies, radiation therapy, and targeted therapies can produce acute side effects or lasting adverse consequences on the heart and circulatory system, making the field of cardio-oncology increasingly important in effective patient care. Cardio-Oncology Practice Manual is a comprehensive, portable guide that provides practical approaches to assessment and management of cardiovascular diseases due to the effects of cardiotoxic agents and treatments. Part of the Braunwald family of renowned cardiology references, it clearly presents clinically relevant aspects of this growing field in one quick, pr...
This book provides comprehensive analysis into individualized patient care, and applying evidence‐based medicine while integrating basic medical knowledge with applied medicine. The Editor and the contributors not only discuss important issues on hypertension management and its deleterious consequences if it is not well‐controlled, but also highlight the important signaling pathways involved in the pathogenesis of hypertensive heart disease and cardiac hypertrophy.
Essential Cardiology: Principles and Practice, 3rd Edition, blends molecular, cellular, and physiologic concepts with current clinical practice and provides up-to-date information on all major aspects of cardiovascular disease. Fully revised by an international panel of leading authorities in the field, it is an authoritative resource for cardiologists, internists, residents, and students. The book presents the clinical examination of the patient, including diagnostic testing and cutting-edge radiologic imaging; pathogenesis and treatment of various types of cardiac abnormalities; the needs of special populations, including pregnant, elderly, and renal-compromised patients; cardiovascular gene and cell therapy; and preventive cardiology. It includes new chapters on cardiovascular disease in women; diabetes and the cardiovascular system; and cancer therapy-induced cardiomyopathy. The Third Edition also focuses on the substantial advances in anti-platelet and anticoagulant therapy; new modalities of cardiac imaging; new anti-arrhythmic drugs; and a sophisticated understanding of vascular biology and atherogenesis.
This book provides a unique, comprehensive, and up-to-date overview of the various NADPH oxidases and narrates the history of their discovery, biochemical characteristics, genetics, molecular structure, and multiple functions in health and disease. It covers the subject in a manner that serves both the expert and the novice researcher in the field. The book starts with an overview of the major milestones in the discovery of the archetypical NADPH oxidase, known as cytochrome b558, and its cytosolic regulators. This is followed by personal recollections by pioneers of the field, descriptions of the work of the major figures of the past by their followers, and a rendering of the history of the...