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Principles of Proteomics
Principles of Proteomics is designed specifically to explain the different stages of proteomic analysis, their complexities and their jargon to students and researchers in a non-technical overview of the field. The author describes the broad range of problems which proteomics can address, including structural proteomics, interaction proteomics, protein modification analysis and functional proteomics. Methodologies are described in user-friendly language, from the more traditional two-dimensional gel electrophoresis to the new developments in protein chip technologies. These are well presented in the context of overall strategies which can be adopted to address the different aspects of large-scale protein analysis.
Principles of Proteomics
Principles of Proteomics, Second Edition, provides a concise and user-friendly introduction to the diverse technologies used for the large-scale analysis of proteins, as well as their applications, and their impact in areas such as drug discovery, agriculture, and the fight against disease. Proteomics is a fast-advancing field in which researchers seek to capture all the proteins in the cell and characterize them in ever more detail. Principles of Proteomics has been fully updated to reflect the most recent developments in the field without losing its focus on the underlying principles. With worked examples, case studies profiling both established and emerging technologies, and further reading lists for each chapter, Principles of Proteomics is an ideal introduction for students, researchers and those working in the industry.
BIOS Instant Notes in Developmental Biology
Coverage of the field in Instant Notes in Developmental Biology is current and focuses largely on the principles of embryonic development. It is designed to provide a clear summary of the principles of developmental biology in a compact and easily manageable structure.
Process Scale Purification of Antibodies
Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing
BIOS Instant Notes in Bioinformatics
The second edition of Instant Notes in Bioinformatics introduced the readers to the themes and terminology of bioinformatics. It is divided into three parts: the first being an introduction to bioinformatics in biology; the second covering the physical, mathematical, statistical and computational basis of bioinformatics, using biological examples wherever possible; the third describing applications, giving specific detail and including data standards. The applications covered are sequence analysis and annotation, transcriptomics, proteomics, metabolite study, supramolecular organization, systems biology and the integration of-omic data, physiology, image analysis, and text analysis.
Gene Transfer to Animal Cells
Gene transfer to animal cells was first achieved more than thirty years ago. Since then, transformation technology has developed rapidly, resulting in a multitude of techniques for cell transformation and the creation of transgenic animals. As with any expanding technology, it becomes difficult to keep track of all the developments and to find a concise and comprehensive source of information that explains all the underlying principles. Gene Transfer to Animals Cells addresses this problem by describing the principles behind gene transfer technologies, how gene expression is controlled in animal cells and how advanced strategies can be used to add, exchange or delete sequences from animal genomes in a conditional manner. A final chapter provides an overview of all the applications of animal cell transformation in farming, medicine and research.
Principles of Genome Analysis and Genomics
With the first draft of the human genome project in the publicdomain and full analyses of model genomes now available, thesubject matter of 'Principles of Genome Analysis and Genomics' iseven 'hotter' now than when the first two editions were publishedin 1995 and 1998. In the new edition of this very practical guideto the different techniques and theory behind genomes and genomeanalysis, Sandy Primrose and new author Richard Twyman provide afresh look at this topic. In the light of recent excitingadvancements in the field, the authors have completely revised andrewritten many parts of the new edition with the addition of fivenew chapters. Aimed at upper level students, it is essential thatin this extremely fast moving topic area the text is up to date andrelevant. Completely revised new edition of an establishedtextbook. Features new chapters and examples from exciting new researchin genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author ofthe new edition of hugely popular Principles of GeneManipulation. Accompanying web-page to help students deal with this difficulttopic at www.blackwellpublishing.com/primrose
Principles of Gene Manipulation and Genomics
The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.
