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Reactive Oxygen Species (ROS) are molecules generated naturally during cellular metabolic processes. They act as signaling agents that oversee specific biochemical pathways, playing a vital role in cell function and survival. However, an imbalance in ROS signaling or excessive ROS production can have harmful effects on the pathophysiology of diseases. ROS are crucial to cell signaling and are involved in various physiological processes. They modulate gene expression, regulate cell cycle progression, and influence immune responses. Although ROS are essential for normal cellular functions, an overabundance of these molecules can lead to oxidative stress, causing DNA damage, lipid peroxidation,...
This open access book, comprising thirty-nine chapters divided into social, cultural, economic, and political spheres, offers a unique opportunity to dive into the complex, dynamic, and sometimes contradictory transformation of Gulf societies in the last few decades. Whilst the Gulf region has at times been seen as impervious to this natural phenomenon of transformation—timeless, never changing, deeply rooted in its ancient tribal customs and traditions and able to blend past and present seamlessly without suffering the wrenching trauma of change—this is clearly not the case, and the region is not immune to the inevitable forces of social change. There is no doubt today that the social c...
Recent growth in knowledge management concepts has played a vital role in the improvement of organizational performance. These knowledge management approaches have been influential in achieving the goal of efficient production of software development processes. Knowledge-Based Processes in Software Development focuses on the inherent issues to help practitioners in gaining understanding of software development processes. The best practices highlighted in this publication will be essential to software professionals working in the industry as well as students and researchers in the domain of software engineering in order to successfully employ knowledge management procedures.
This ground-breaking book focuses on the ‘forgotten refugees’, detailing people with disabilities who have crossed borders in search of protection from disaster or human conflict. The authors explore the intersection between one of the oldest international human rights treaties, the 1951 Convention relating to the Status of Refugees, with one of the newest: the Convention on the Rights of Persons with Disabilities (CRPD). Drawing on fieldwork in six countries hosting refugees in a variety of contexts – Malaysia, Indonesia, Pakistan, Uganda, Jordan and Turkey – the book examines how the CRPD is (or should) be changing the way that governments and aid agencies engage with and accommodate persons with disabilities in situations of displacement. The timeliness of the book is underscored by the adoption in mid-2016 of the UN Charter on Inclusion of Persons with Disabilities in Humanitarian Action adopted at the World Humanitarian Summit.
This handbook provides comprehensive coverage of the role of proteases and the associated biochemical pathways in cancer development and metastasis. Proteases make up about 2% of the human genome and play a critical role in the tumor microenvironment. Handbook of Proteases in Cancer: Cellular and Molecular Aspects introduces the major classes of proteases and the signal transduction mechanisms associated with cancer initiation and progression. It discusses the role of inflammation and immune responses in proteases-induced cancer. The book covers cancer-induced gene expression and apoptotic and necrotic pathways in cancer. This is useful for researchers and professionals in cancer research, b...
ARTIFICIAL INTELLIGENCE FOR RENEWABLE ENERGY AND CLIMATE CHANGE Written and edited by a global team of experts in the field, this groundbreaking new volume presents the concepts and fundamentals of using artificial intelligence in renewable energy and climate change, while also covering the practical applications that can be utilized across multiple disciplines and industries, for the engineer, the student, and other professionals and scientists. Renewable energy and climate change are two of the most important and difficult issues facing the world today. The state of the art in these areas is changing rapidly, with new techniques and theories coming online seemingly every day. It is importa...
"This book is the best source for the most current, relevant, cutting edge research in the field of industrial informatics focusing on different methodologies of information technologies to enhance industrial fabrication, intelligence, and manufacturing processes"--Provided by publisher.
Profiles of 102 eminent Muslims of India from various fields.
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)