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Mechanobiology
Until the '90s, research in biomechanics and biorheology mainly focused on tissues and cell priorities, so as to identify the bioclinical problems linked to the rheology properties of cells and tissues or to develop substitutes. Advances in molecular biology and new knowledge in cellular biology over the last ten years have given access to a more physiological approach to the effects of stress on cells and tissues.
Grasslands
This book looks at significant current grassland problems and issues, and provides an insight into grassland productivity in diverse areas of the world, with their various production systems. There is a focus on recent technical advances and the prospects for further innovation, through twenty-one chapters by eminent grassland scientists, grouped into seven sections - forage germplasm; forage conservation; grass-based systems and organic production; climate change, biodiversity and biotechnology; geographical information systems; farmer and pastoralist participation; and regional developments. The book is timely in view of the expanding human and livestock populations, especially in arid and semi-arid environments, with the consequent pressure on the world's grasslands.
Grassland: a global resource
"The concept of grasslands as a global resource is not new. Indeed many recognised authorities have been canvassing for a global approach to understanding, managing and exploiting this resource for many years. This is the first book that gathers together leading experts from around the world to outline our current understanding of this complex ecosystem, the ways in which it can be enhanced and utilised and where the research challenges are for the future. The following themes unite the book: - Efficient production from grassland; - Grassland and the environment; - Delivering the benefits from grassland. The reader is given an in depth understanding of the biology of the system and how grass...
Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life
This book includes the most essential contributions presented at the 17th Evolutionary Biology Meeting in Marseille, which took place in September 2013. It consists of 18 chapters organized according to the following categories: · Molecular and Genome Evolution · Phylogeography of Speciation and Coevolution · Exobiology and Origin of Life The aims of the annual meetings in Marseille, which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research, are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering an overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.
Polyploidy and Genome Evolution
Polyploidy – whole-genome duplication (WGD) – is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryotes seems closely tied to multiple WGDs. Polyploidy generates new genomic interactions – initially resulting in “genomic and transcriptomic shock” – that must be resolved in a new polyploid lineage. This process essentially acts as a “reset” button, resulting in genomic changes that may ultim...
Fungal Pathogenesis
Stresses molecular and biochemical studies of opportunistic and frank fungal pathogens! This book gives a comprehensive overview of human pathogenic fungi that offers a current and concise survey of virulence factors, host responses and recognition, treatment and diagnosis of infections, invasive enzymes, intracellular survival, morphogenesis, adaptation, and properties of major fungal pathogens that contribute to disease. Focuses on human fungal infections, including candidiasis, pneumocystosis, aspergillosis, and cryptococcosis. With over 3700 references to accommodate continuing study, Fungal Pathogenesis covers natural and acquired immunity, vaccine development, and immune reconstitution...
Principles of Osteoarthritis
This volume addresses the nature of the most common form of arthritis in humans. If osteoarthritis is inevitable (only premature death prevents all of us from being afflicted), it seems essential to facilitate its recognition, prevention, options, and indications for treatment. Progress in understanding this disease has occurred with recognition that it is not simply a degenerative joint disease. Causative factors, such as joint malalignment, ligamentous abnormalities, overuse, and biomechanical and metabolic factors have been recognized as amenable to intervention; genetic factors, less so; with metabolic diseases, intermediate. Its diagnosis is based on recognition of overgrowth of bone at joint margins. This contrasts with overgrowth of bone at vertebral margins, which is not a symptomatic phenomenon and has been renamed spondylosis deformans. Osteoarthritis describes an abnormality of joints, but the severity does not necessarily produce pain. The patient and his/her symptoms need to be treated, not the x-ray.
