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Since the pioneering pharmacotherapy for treatment of schizophrenia in the 1950s by antipsychotics, only a few major innovations have been made, pointing to a general stagnation in the field of pharmacology of schizophrenia. Drug Discovery for Schizophrenia covers new insights in the field of schizophrenia with an aim to advance the understanding of scientists and clinicians in this area and to fuel drug discovery. The book outlines a change in the way schizophrenia is treated by moving away from focusing only on treating symptoms in patients. Innovative drugs emerge from deeper comprehension of the pathological processes that emerge earlier in life, hence, providing strategies for preventative therapy to alter the course of this mental disorder. Amongst other current topics, the book covers new findings in genetics and epigenetics, progress in animal models for schizophrenia and the usage of induced pluripotent stem cells. The combination of these important areas benefit psychiatric neuroscience, filling the gaps in the knowledge of neurobiology of schizophrenia and providing novel perspectives for future drug development.
Provides a step-by-step process for implementing an aggressive career search that includes job-winning resumes and cover letters, mastering the interview, and negotiating job offers.
Opportunities to enter a spiritual place are all around us, but we often don't recognise them. Pause - A Spiritual Power helps the reader identify those moments and enter places of spiritual pause. The spiritual life, often neglected, exists apart from our thoughts and feelings. Pause explores how spirituality is separate and how we often mistakenly substitute rational and emotional experiences for spiritual experience. To be spiritual is not to be religious or bound to a specific understanding of God. To be human is to have a spirit within, regardless of religious commitment or persuasion. Attending to one's spiritual life, finding pause, is not confined or defined by any one faith traditio...