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GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!
Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC
This college-level handbook offers a comprehensive and accessible overview of sociological and cultural perspectives on the human body. Organized along the lines of a standard anatomical textbook delineated by body parts and processes, this volume subverts the expected content in favor of providing tools for social and cultural analysis. Students will learn about the human body in its social, cultural, and political contexts, with emphasis on multiple, contested meanings of the body, body parts, and systems. Case studies, examples, and discussion questions are both US-based and international. Advancing critical body studies, the book explicitly discusses bodies in relation to race, class, gender, sexuality, ability, age, health, geography, and citizenship status. The framing is sociological rather than biomedical, attentive to cultural meanings, institutional practices, politics, and social problems. The authors use commonly understood anatomical frames to discuss social, cultural, political, and ethical issues concerning embodiment.
Plasticity establishes a permanent connectivity of the synapses in more rigid networks, which when excited, all will communicate together. Elasticity maintains an instant connectivity between neural networks by bringing synapses in a suitable communication distance. The other way of internal communication in brain is through the nerve fibers when two neural network configurations in a far distance can resonate together. The integration of these types of communications is the mean that the brain functions.
The book is a history of the McKnight Endowment Fund for Neuroscience and an assessment of its effectiveness in advancing neuroscience. The book discusses the Fund's early and steady commitment to basic science as well as it's tradition of leveraging relatively modest dollars to make a big difference in careers and the field overall. The fund exists strictly to give awards and create a community of peers through an annual conference dedicated to research. In near unison, scientists who have received awards say they were able to test a risky idea, get their career off the ground, or make a significant change in their career because of McKnight's flexible dollars. The book consists of three parts: (1) origins--including both the funder and the scientists who shaped the program; (2) a review of the science to show how McKnight awardees have advanced the field; and (3) 10 keys to success. We also have an interview with Julius Axelrod (one of the early advisors, done shortly before his death in 2004) and stories of how awardees used their McKnight grants, plus other information.
Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuro...
Presents an overview of the use of legal and illegal drugs, its history, its legal status, its impact on society, as well as the treatment and prevention of drug abuse.
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This collection studies the representations of the character of the monarch in literature and cinema. Being a person, an institution, a character archetype and a narrative role, the characters of the monarch and other royal or regal characters oscillate between humanity and the non-human. As such, they are hybrid forms of existence and subjectivity. The authors of this collection explore this hybridity across large spectra of genres, historical periods and cultural contexts. Some of the most prolific and widely read scholars analyze the archetype of the monarch on the page, the stage and the screen. They cover large swathes of intersecting creative and interpretive territories including ancient epic and religious poetry, Arthurian legends, British Renaissance and modern drama, British horror films and Hollywood crime and sports films. This collection also features interviews with six prominent comic book writers and artists, who discuss the influence of classical royal archetypes on their works.
Uncovers the influences that have conditioned people to overeat, explaining how combinations of fat, sugar, and sa