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Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
Approximately three percent of newborn humans have congenital anomalies with significant cosmetic and/or functional consequences. Much of our ability to understand what has gone awry in these birth defects rests with development of animal models for them; the mouse has emerged as the model organism of choice for these studies. This volume reviews mouse models of specific developmental genetic diseases, including neural tube defects; cleft lip and/or palate; congenital heart disease; ciliopathies; hereditary deafness and others to provide conceptual insight into congenital anomalies generally. The interplay between clinical observation and murine model systems is expected to yield deep insigh...
Together with other volumes in this series, Volume 53 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development. This volume in particular will be essential reading for anyone interested in stem cells, signaling, medical implications of developmental determinants, hematopoeisis, axis specification, and molecular genetics of development. - Includes a landmark review on Hedgehog genes and their gene products in invertebrate and vertebrate development - Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine - The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
This new volume of the renowned serial Current Topics in Developmental Biology covers the important features of growth factors in development. With an international board of authors, this volume will be invaluable for researchers in cell, developmental and molecular biology. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - This volume provides an up-to-date and timely perspective
Centrosomes play an integral role in the growth of cells and the ultimate development of many animals, and sometimes plants. In addition to the normal growth of cells, centrosomes can also play a key role in the spread of cancer and are of increased interest to both the genetics and oncology communities. Volume 49 of Current Topics in Developmental Biology will present all known research surrounding the centrosome, across a variety of systems, will be well referenced, and speculate where the research is headed. - Discusses centrosomes and cancer, centrosomes and early development, and molecular biology of the centrosome - Heavily illustrated, with many color figures - Chapters written by international leaders in the field
The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research
Identifying the Mayan World Tree with the central axis of the cosmos, the author shows how evolution is not random • Shows how the evolution of the universe emanates from the cosmic Tree of Life • Explains the origin and evolution of biological life and consciousness and how this is directed Using recent findings within cosmology, coupled with his broad understanding of the Mayan Calendar, biologist Carl Johan Calleman offers a revolutionary and fully developed alternative to Darwin’s theory of biological evolution--and the theory of randomness that holds sway over modern science. He shows how the recently discovered central axis of the universe correlates with the Tree of Life of th...
This compendium provides a concise and up-to-date assessment of critical recent issues related to erythroid biology. Developmental, epigenetic, methodological, biochemical, and clinical aspects are integrated to provide a powerful overview of their interrelationships and importance to the generation of the red cell. The excitement generated by these novel observations and the anticipation of future directions in studies of the red cell is a highlight of this volume. *The first comprehensive volume covering the breadth of the topic *The latest advancements that lead to novel directions in the study of red cells *An informative discussion of red cells as they relate to the essential oxygen-carrying component of the body
Published in affiliation with the Society for Developmental Biology.
There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This volume (complemented by the forthcoming companion volume by Cassimeris and Tran) brings together current research and protocols in the field of microtoubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. - Chapters reflect both experimental procedures and new developments in the field of microtubule in vitro research - Combines classical approaches and modern technologies - Presents easy-to-use protocols and thorough background information, compiled by leaders in the field