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Molecular Signatures of Infectious Agents in Cancer
The Cancer Biomarkers Research Group (CBRG) of the Division of Cancer Prevention (DCP), National Cancer Institute, sponsored a workshop entitled Molecular Signatures of Infectious Agents in Bethesda, Maryland, September 7 - 8, 2000, to identify molecular signatures of infectious agents and to utilize this information for risk assessment and development of prevention strategies against these infectious agents. The specific objectives of the workshop were to review state-of-the-science in detection technology that can identify extraneous genomic insertion in human cancers and to establish future research directions for using the molecular signatures of infectious agents for early detection, risk assessment and prevention of cancer.
DNA Tumor Viruses
This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Human Cancer Viruses
The first identification of a tumor-causing virus, Rous sarcoma virus, occurred almost 100 years ago, but it was not until the 1970s that the genetic basis for oncogenesis by this and other acutely transforming retroviruses was appreciated. Since then, numerous viral oncogenes and their corresponding cellular proto-oncogene counterparts have been identified, and these studies have contributed much to our understanding of crucially important aspects of cell biology and transformation.This book provides an up-to-date overview of the 6 major viruses that cause human cancers - HPV, HBV, HCV, EBV, KSHV and HTLV-1 - with respect to their molecular biology and epidemiology and to clinical aspects of disease, therapy and prevention. Contributed by over a dozen internationally renowned scientists, the chapters are comprehensively written and illustrated. The book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to understand the mechanisms leading to cellular transformation and oncogenesis by these viruses as a basis for the development of specific therapeutic and antiviral treatments.
Cancer Control
Cancer control is the term applied to the development of integrated population-based approaches to reduce the incidence and mortality from cancer and to minimize its impact on affected individuals and on the community. The integrated nature of cancer control is reflected in this multi-disciplinary text, the first in this rapidly developing field.
Labor Cases
A full-text reporter of decisions rendered by federal and state courts throughout the United States on federal and state labor problems, with case table and topical index.
Immunization Safety Review
The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
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