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This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliat...
Since World War II, aesthetic impulses generated in Italy have swept through every film industry in the world, and in her book Mira Liehm analyses the roots in literature, philosophy, and contemporary Italian life which have contributed to this extraordinary vigor. An introductory chapter offers a unique overview of the Italian cinema before 1942. It is followed by a full and profound discussion of neorealism in its heyday, its difficult aftermath in the fifties, the glorious sixties, and finally by an analysis of the contemporary cinematic crisis. Mira Liehm has known personally many of the leading figures in Italian cinema, and her work is rich in insights into their lives and working methods. This impressive scholarly work immediately outclasses all other available Italian film histories. It will be essential reading for anyone seriously interested in the cinema.
Thyroid hormone is important for controlling metabolism and many other body functions. Changes in thyroid hormone physiology, its regulation and diseases thereof have been a concern for the mankind. Understanding of the thyroid hormone(s) has been continuously updated and revised. The contributions from different authors have been incorporated in this book for this purpose. The original work of these contributors will be especially useful in furthering the knowledge on thyroid and help in creating new vistas of research.
The IGF system pervades the fields of development, linear and cellular growth and metabolism. Not only is the functional integrity of the IGF system crucial for normal linear growth and metabolism, it is also of fundamental importance for normal fetal development. This book consists of a compilation of chapters based on presentations at a symposium entitled 'IGFs and IGFBPs: Assessment and Therapeutic Benefit'. Highly qualified basic scientists and endocrinologists report new advances in the broad field of IGF physiology and pathophysiology, related to clinical medicine. New and topical areas of the IGF field are covered, focussing particularly on clinically relevant topics related to growth...
Carlo Testa demonstrates that while pairings of famed directors and writers are commonplace in modern Italian cinema, the study of the interrelation between Italian cinema and European literature has been almost completely neglected in film scholarship.
This book is an in-depth analysis of three of the most crucial years in twentieth-century Italian history, the years 1943-46. After more than two decades of a Fascist regime and a disastrous war experience during which Italy changed sides, these years saw the laying of the political and cultural foundations for what has since become known as Italy's First Republic. Drawing on texts from the literature, film, journalism, and political debate of the period, Antifascisms offers a thorough survey of the personalities and positions that informed the decisions taken in this crucial phase of modern Italian history.
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The history of cinema, and notably that of post-war Italian cinema, can only be understood adequately in the context of other contiguous cultural disciplines. World literature, including that of France, Germany, and Russia, played a key role in the development of post-war Italian film and the cinematic technique it has come to embody. Moving away from the usual modes of defining this period—a trajectory that begins with neorealism and ends with Bertolucci—author Carlo Testa offers proof that coming to terms with literary texts is an essential step toward understanding the motion pictures they influenced. The means of recreating literature for the screen has changed drastically over the last half-century, as has the impact of different national traditions on Italian cinema. Testa's work is the first to explicitly and deliberately link postwar Italian cinema to general intellectual concerns such as the relationship between literary authors and cinematic auteurs. Moreover, his analysis of the impact of French, German, and Russian cultures on Italy brings forth a new reading of Italian cinema, a new paradigm for exploring complex issues of authorship, culture, and art.
This unique issue examines the changes in endocrine function that occur with aging. Topics discussed include testosterone deficiency in older men, aging somatropic axis mechanisms, aging hypothalamo-pituitary-ovarian axis, and thyrotopic axis adaptations.