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Neuronal mechanisms of epileptogenesis
Several types of brain injuries are causes of acquired temporal lobe epilepsy (TLE). The seizure-free "latent period" that often follows the brain injury is of unknown mechanistic significance but is commonly considered as the "epileptogenic" period characterized by gradual pathogenic processes leading to the onset of clinically detectable epilepsy. Acute convulsive status epilepticus (SE) is often associated with an adverse developmental outcome characterized by learning disabilities related to the cumulative effects of seizures and development of TLE. The symptomatic manifestations of TLE appear only after a widespread irreversible damage of entorhinal cortex, and hippocampus, the brain ar...
Dependable Computing - EDCC 2005
It is always a special honor to chair the European Dependable Computing C- ference (EDCC). EDCC has become one of the well-established conferences in the ?eld of dependability in the European research area. Budapest was selected as the host of this conference due to its traditions in organizing international scienti?c events and its traditional role of serving as a meeting point between East and West. EDCC-5 was the ?fth in the series of these high-quality scienti?c conf- ences. In addition to the overall signi?cance of such a pan-European event, this year’s conference was a special one due to historic reasons. The roots of EDCC date back to the moment when the Iron Curtain fell. Originall...
Sleep and Chronobiology in Plasticity and Memory
Chronobiological mechanisms regulating time-of-day mediated behaviors, such as sleep and circadian rhythms, are thought to interact with and/or share cellular and molecular signaling cascades that shape synaptic plasticity and neural excitability. These same factors are also known to underlie events that govern higher-order cognitive processing, including learning and memory formation, and often through phylogenetically conserved pathways. This suggests that factors which contribute to adaptive responses to changing environmental stimuli are likely derived from basic evolutionarily ancient processes, and underscores the importance of using both invertebrate and vertebrate models to study the interaction of chronobiology and cognitive processing. This issue highlights current views along with original research on sleep and circadian features of plasticity and memory in multiple species, models, and systems.
Spontaneous Generation of Neurospheres from Mouse Embryonic Stem Cells
Spontaneous Generation of Neurospheres from Mouse Embryonic Stem Cells.
Cannabis Pharmacy
The most comprehensive and approachable book available on understanding and using medical marijuana. Revised and updated with the latest information on varietals, delivery, dosing, and treatable conditions, Cannabis Pharmacy is "a well-designed and -illustrated and easy-to-use resource"(Booklist) for those considering medical marijuana as a treatment option. In Cannabis Pharmacy, expert Michael Backes offers evidence-based information on using cannabis to treat an array of ailments and conditions. He provides information on how cannabis works with the body's own system, how best to prepare and administer it, and how to modify and control dosage. This newly revised edition is now completely u...
