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Molecular Mechanisms of Spondyloarthropathies
It is now over ten years since we edited the first edition of HLA-B27 in the Development of Spondyloarthropathies (SpA). It is obvious that over this period an enormous amount of information concerning SpA and HLA-B27 has accumulated, and this has been reflected in the knowledge of molecular mechanism of the spondyloarthropathies. Discussion for such a book took initial form at the outstanding 4th Gent Symposium on SpA in October 2006, but was not formally commissioned by Landes Bioscience until early 2007. Molecular Mechanisms of Spondyloarthropathies aims to synthesize this growing knowledge and present all the current studies concerning the basic research of SpA. Over the last decade, eno...
Pharmaceutical Biotechnology
Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to ...
Development and Engineering of Dopamine Neurons
Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of d...
Mosaics in Mexico
The author presents the history evolution of the mosaic production since ancient Greek and Roman tiles and Pre-Columbian mosaic pieces along the history of "Mosaicos Venicianos de Mexico", a factory and workshop owned and operated by the Perdomo family for over 50 years. In the workshop located in Cuernavaca (state of Morelos, Mexico) several generations of mosaicists have produced glass Byzantine mosaic tiles while upholding the highs tandards of the traditional craft of the tesserae with extraordinary examples of contemporary mosaic art displayed in murals and architectural ornamentation. The company has participated with artists Jose Chavez Morado, Diego Rivera, Juan O'Gorman, David Alfaro Siqueiros and Francisco Eppens amongst others in the creation of monumental public mosaic murals"--Provided by vendor.
Handbook of Global Environmental Politics
The book s greatest strength is the range and theoretical ambition of its contributions to regime theory, governance, and international cooperation. . . Recommended. Graduate students, researchers, and faculty. D.L. Feldman, Choice The first Handbook of original articles by leading scholars of global environmental politics, this landmark volume maps the latest theoretical and empirical research in this young and growing field. Captured here are the dynamic and energetic debates over concerns for the health of the planet and how they might best be addressed. The introductory chapters explore the intellectual trends and evolving parameters in the field of global environmental politics. They ma...
Target Pattern Recognition in Innate Immunity
Target pattern recognition in innate immunity is responsible for the immediate, usually protective, responses shown against invading microorganisms, and it is the principal feature of self and non-self recognition by virtue of the recognition of structures on the microbial pathogens, which are not found on host cells. This is an area that has been very actively researched, over approximately the past 12 years, and therefore this volume provides a timely comprehensive, and up to date, summary of the types and range of cell surface, intracellular, and secreted, host proteins involved in the recognition of microbial products, and of the protective mechanisms triggered as a result of the recogni...
