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The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term “globesity” to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has to date often been unachievable and unaffordable outside of established bariatric centers, but such centers themselves usually have insufficient capacity and resources to cope with the demand among the general population. This book therefore provides a wealth of guidance and helpful tips and tricks on how to deal with obese patients within a general surgery setting. Importantly, it highlights the need for global rethinking on public health as regards resource allocation and patterns and standards of care, with the ultimate goal of improving outcomes through greater affordability.
This book describes in detail the multidisciplinary management of obesity, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical exercise, psychological issues, nutritional strategies, pharmacological options and bariatric surgery. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of obesity, which has rapidly become a major public health problem.
Far from a sign of healthy prosperity and contentment, overweight and obesity are now considered high risk factors for a wide range of diseases including early death and disability, heart disease, diabetes, reproductive problems, cancer, breathing problems and arthritis. Obesity, now at epidemic levels in many countries, is defined as an excessively high amount of body fat or adipose tissue in relation to lean body mass. The amount of body fat (or adiposity) includes concern for both the distribution of fat throughout the body and the size of the adipose tissue deposits. This book includes within its scope the causal connection of obesity to diseases as well as the prevention and treatment of obesity. Leading-edge scientific research from throughout the world is presented.
The American Obesity Association identifies obesity's link to numerous medical conditions, including hypertension, type 2 diabetes, cardiovascular disease, several cancers, and a host of inflammatory disorders. Evidence indicates that inflammation has more than a corollary relation with obesity; that in fact, obesity itself manifests a low-grade, m
Extraordinary advances in the understanding of the links between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of knowledge in the field. As a result, it is now imperative that clinicians who care for patients with CVD or its key risk factors have a solid understanding of the often complex interrelationships between cardiovascular health and chronic diseases such as diabetes and obesity. Written by a team of international thought leaders in cardiology, endocrinology, diabetology and nutritional science, this important new book: Examines and updates the role of obesity, hyperlipidemia, diabetes, hypertension, thrombosis, and aging in atherogenesis De...
Neurological and psychiatric disorders can occur in endocrine diseases either in the setting of the clinical manifestations of the same (i.e., hyper- or hyposecretion of hormones or peptides from the endocrine glands) or as events secondary to the pathogenetic mechanisms of the endocrinopathy (i.e., autommunity affecting endocrine glands and the brain). Also the medical or surgical treatment of the endocrine disease can sometimes determine the occurrence of neurological or psychiatric abnormalities. Moreover some genetic alterations can lead to syndromes affecting both the endocrine and the nervous system with a variety of possible manifestations. In the last couple of decades a number of as...
These guidelines make recommendations regarding the management of individuals with a body mass index greater than 25.0 kg/m2 and cover all age groups, from children to the elderly, as well as various patient subsets. A range of measures to yield health benefits are set out, including healthy eating plans, increased physical activity, and behavioral modifications to help patients to manage obesity. In addition, recommendations are made on the use of bariatric surgery and the new antiobesity drugs. Throughout the process of developing the recommendations, every attempt was made to ensure use of a rigorous, evidence-based approach. The guidelines are promoted by the Italian Society of Obesity (SIO) and were formulated in compliance with a prespecified process overseen by a steering committee. They are intended for use by a wide range of clinicians, including general practitioners, primary health care nurses, and primary health care professionals, and will hopefully prove of value in combating the obesity epidemic not only in Italy but across Europe and elsewhere in the world.
This volume analyses maritime decarbonization from various perspectives. It contains unique approaches and tools in four areas: scenarios, value chains, enablers, and partnerships. Decarbonization has become a very important focus in the maritime industry. Anyone that delves into the topic quickly appreciates its breadth and complexity. Minimizing greenhouse gases (GHG) emissions in maritime practices at large and doing it swiftly is far from simple. The Paris 2015 climate goals and the IMO ambitions may be the industry’s guiding lights. But is this enough? Probably not. At the managerial level a paradigm shift is needed: from a fixed mindset that is calling for compensation to a growth mi...
This is a book that handles the non-alcoholic fatty liver disease from the bio-statistical point of view . The statistical method used is Continuous Time Markov Chains ( CTMCs) utilizing the MLE and quasi-Newton method to estimates the transition rate matrix , once obtained , the transition probability matrix can be estimated by exponentiation of this rate matrix. The transition probability matrix can also be obtained by solving forward Kolmogorov differential equations which yields more stable solution than the matrix exponentiation. The rate probability matrix can then be used to estimate the number of patients in each stage of the disease process as well as the life expectancy in each sta...
This book is a printed edition of the Special Issue "Vitamin E" that was published in Antioxidants