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How engineered materials and machines powered by living biological cells can tackle technological challenges in medicine, agriculture, and global security. You are a biological machine whose movement is powered by skeletal muscle, just as a car is a machine whose movement is powered by an engine. If you can be built from the bottom up with biological materials, other machines can be as well. This is the conceptual starting point for biofabrication, the act of building with living cells--building with biology in the same way we build with synthetic materials. In this volume in the MIT Press Essential Knowledge series, Ritu Raman offers an accessible introduction to biofabrication, arguing tha...
This 1997 text is a guide to acute liver failure aetiology, pathology and treatment.
This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. The use of biomarkers is growing, with a steady stream of products being brought out by the pharmaceutical industry. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options. However, in many cases the evidence which supports the use of these methods as opposed to traditional biochemical tests has not yet been demonstrated, and it is intended that this volume will help clarify the strengths and weaknesses of using these biomarkers across a wide range of applications and in the various organs of the body. This approach will provide pathologists, clinical biochemists and medical laboratory scientists with an invaluable overview of the diverse applications of biomarkers in medicine.
Since ancient times, plants serve as a valuable source of traditional herbal medicines. Unlike modern medicines, herbal medicines have consistently demonstrated health advantages, including a lack of serious adverse side effects, long-lasting curative impacts and overall cost-effectiveness. Even today, with various modern pharmaceutical medicines commonly available, plant-based medicines and aromatics are increasingly in demand throughout the health sector globally, where they are used not only for the treatment of disease, but also, preventatively for maintaining good health. People are seeking alternatives to modern medical treatments turning to phytomedicine for primary health care. Howev...
Cell culture is cell cloning technology that simulates in vivo environment conditions such as asepsis, appropriate temperature, and pH as well as certain nutritional conditions to enable cells to survive, grow, reproduce, and maintain their structure and function. Cell culture can be used to grow human, animal, plant, and microbial cells. Each type of cell culture has its own characteristics and essential conditions. This book focuses on the advanced technology and applications of cell culture in the research and practice of medical and life sciences. Chapters address such topics as primary cancer cell cultures, 2D and 3D cell cultures, stem cells, nanotechnology, and more.
As membrane trafficking research has expanded over the past thirty years, a remarkable convergence of information has been gained by using genetic approaches in yeast cells with biochemical approaches in mammalian cells. This book reflects these advances by devoting one section of the book to yeast cells and the other to mammalian cells, with each section providing both classic and cutting-edge techniques to study macromolecular transport across the membranes.
A broad range of medical and surgical details of pediatric liver disease and liver transplantation Great progress in molecular biology, therapeutics, imaging as well as surgery have vastly improved the understanding and treatment of childhood liver disorders. In particular, surgical advancements in liver transplantation currently allow for a lower age or weight limit for recipients. Furthermore, the majority of children with liver disease or with liver transplantation today survive well into adulthood. In this book, world experts in the now established subspecialty of pediatric hepatology provide a comprehensive summary of the latest advances in pathophysiology, molecular diagnostics and treatment strategies. Day-to-day management of liver transplant recipients as well as psychosocial aspects and complications during the challenging transition phase to adulthood are discussed in detail. This up-to-date overview will be an invaluable tool for trainees in pediatric gastroenterology, a ready reference for busy clinicians and nurses or allied health professionals involved in the care of children with liver disease and after liver transplantation.
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Human cell culture is not a new topic, but the development of new molecular techniques and reagents which can be used to investigate cell function and the responsible intracellular mechanisms make it a continuing requirement. This third edition of Human Cell Culture Protocols expands upon the previous editions with current, detailed protocols for the isolation and culture of a range of primary cells from human tissues. With new chapters on pancreatic cells needed for basic studies on the pathogenesis of diabetes and for their application for islet transplantation, the book also delves into protocols for hepatocytes, skin cells, lung cells, parathyroid cells, gastric cells, renal cells, adipo...