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In this explosive "New York Times" bestselling follow-up to "Hawke," secret agent Alexander Hawke receives word that someone is systematically murdering American diplomats and their families around the globe. On the trail of two killers, Hawke must stop a terrorist attack from crippling the nation.
In August 1680 the Pueblo Indians of northern New Mexico arose in fury to slay their Spanish colonial overlords and drive any survivors from the land. Andrew Knaut explores eight decades of New Mexican history leading up to the revolt, explaining how the newcomers had disrupted Pueblo life in far-reaching ways - they commandeered the Indians’ food stores, exposed the Pueblos to new diseases, interrupted long-established trading relationships, and sparked increasing raids by surrounding Athapaskan nomads. The Pueblo Indians’ violent success stemmed from an almost unprecedented unity of disparate factions and sophistication of planning in secrecy. When Spanish forces retook the colony in the 1690s, freedom proved short-lived. But the revolt stands as a vitally important yet neglected historical landmark: the only significant reversal of European expansion by Native American people in the New World.
The development of hypothesis of oxidative stress in the 1980s stimulated the interest of biological and biomedical sciences that extends to this day. The contributions in this book provide the reader with the knowledge accumulated to date on the involvement of reactive oxygen species in different pathologies in humans and animals. The chapters are organized into sections based on specific groups of pathologies such as cardiovascular diseases, diabetes, cancer, neuronal, hormonal, and systemic ones. A special section highlights potential of antioxidants to protect organisms against deleterious effects of reactive species. This book should appeal to many researchers, who should find its information useful for advancing their fields.
Reports, orders, journals, and letters of military officials trace frontier history through the Chicimeca War and Peace (1576-1606), early rebellions in the Sierra Madre (1601-1618), mid-century challenges and realignment (1640-1660), and northern rebellions and new presidios (1681-1695).
This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.
Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds, UK during the summer of 2014. As such this volume represents a unique collection of state of the art reviews and original, brief research articles covering all aspects of oxygen sensing, ranging from the molecular mechanisms of chemotransduction in oxygen sensing cells such as the carotid body type I cells, to the adverse, reflex cardiovascular outcomes arising from carotid body dysfunction as seen, for example, in heart failure or obstructive sleep apnoea. This volume will be of tremendous interest to basic scientists with an interest in the cellular and molecular biology of oxygen sensing and integrative, whole organism physiologists as well as physicians studying or treating the clinical cardiovascular consequences of carotid body dysfunction.
Reprint of the original, first published in 1884.