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CARDIAC VALVE ALLOGRAFTS (HOMOGRAFTS) highlights the current controversy about freehand subcoronary aortic valve and root replacement with regard to postoperative morbidity and long term durability. It discusses particular implantation techniques of preference in young patients and in different root pathology. Other chapters address intermediate- and long-term results on cardiac valve and vascular homografts for treating complicating cardiac valve and aortic infections. The chapter on basic science additionally makes this book a highly authoritative reference source for cardiac surgeons, physicians and scientists. This work provides a current survey of the state-of-the-art.
Historical Introduction The Marfan Syndrome: From Clinical Delineation to Mutational Characterization, a Semiautobiographic Account VictorA. McKusick l n 1876, E. Williams, an ophthalmologistin Cincinnati, Ohio, described ectopia lentis in a brother and sister who were exceptionally tall and had been loosejointed from birth. I Although there is a Williams syndrome that has aortic manifestations (supravalvar aortic stenosis), the name Williams was never associated with the disorder we now call Marfan syndrome. The reason is clear: Williamswas geographically removed from the leading medical centers and published in the Transactions of the American Ophthalmological Society; surely his report at...
This global-perspective guidebook explores issues related to organ donation in various countries, including the United States, Spain, Australia, India, and Pakistan. Readers will learn about poverty and organ donation, illegal trafficking of organs, and compensation for donation. This book also examines the presumed consent of opt-in / opt-out laws. Essay sources include The Portugal News, Ami Cholia, Calev Ben-David, Habib Toumi, and Natsuko Fukue.
MASTERING STRUCTURAL HEART DISEASE A COMPREHENSIVE AND IN-DEPTH GUIDE TO MANAGING THE TREATMENT OF STRUCTURAL HEART DISEASE In Mastering Structural Heart Disease, a team of distinguished experts in interventional cardiology deliver a complete and robust explanation of nearly all present-day structural heart disease devices, their appropriate uses, and technical tricks to help ensure treatment success. The text is written in a Socratic, “question-and-answer” format which is designed to help readers absorb and retain knowledge. Online clinical cases and vignettes supplement the material in the book, providing a comprehensive overview of the subject. The authors combine the latest technique...
This text describes and illustrates with some 700 detailed anatomic and surgical drawings the whole spectrum of surgical procedures employed to treat acquired and congenital diseases of the heart and great vessels in adults and children. A rather traditional chapter on history of cardiac surgery precedes chapters dedicated to quality improvement, followed by ICU management in adult and pediatric cardiac surgery, and techniques of extracorporeal circulation in both age groups. Further special topics are cardiovascular tissue engineering, minimally invasive cardiac surgery, endovascular treatment of aortic diseases, and cardiac assist devices, including total artificial heart. Written by 71 internationally recognized experts from 40 cardiac units in Central Europe and North America, this book will be invaluable not only for both novice and experienced surgeons, but also for all physicians, nurses, and technicians caring for patients with heart disease of any type, at any age.
Marfan Syndrome is a hereditary disorder of connective tissue which primarily affects the eyes, skeleton, blood vessels, and various structures of the heart. Since 1943, when the cardiovascular manifestations of Marfan Syndrome were first described, understanding of its nature, diagnostic tools, and surgical treatment have been remarkably improved. Although the specific surgical procedures have reached an advanced standard and general acceptance, many questions remain unanswered and have given rise to ongoing controversy. Cardiovascular Aspects of Marfan Syndrome presents the advances in understanding the cause and pathogenesis of Marfan Syndrome and its current specific surgical therapy.
It was the genius of Gordon Murray in Toronto that introduced the use of allografts into cardiac surgery in the 1950s. Soon after this on opposite sides ofthe world, Sir Brian Barratt-Boyes in Auckland, New Zealand, and Mr. Donald Ross in London, undertook to use allografts for the replacement of diseased aortic valves. Since that time the global interest in allografts has been patchy, episodic, and without a con sensus. Nonetheless, for the last 20 years at least three groups in the world have steadfastly pursued the development of new and relevant information concerning the use of allograft valves in humans. These are the centres of Sir Brian Barratt Boyes, Mr. Donald Ross, and Mark O'Brie...
"Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensi...
The study of stem cell research has recently gained the attention from a growing, multidisciplinary community of scientist; this exponential growth of interest is driven by the hope of discovering cures for several diseases through transplantation medicine. Trends in Stem Cells Biology and Technology aptly serves this developing community as it reveals new aspects of stem cell research by specifically covering studies focused on spermatogonial stem cells, uniparental embryonic stem cell lines, the generation of gametes from stem cells, reprogramming germ cells to stem cells, nuclear and somatic cell genetic reprogramming, tissue engineering and mechanotransduction of stem cells and finally the development of stem cell technologies for the treatment of deafness, heart disease, corneal injury and diabetes. With contributions by leading scientists and renowned scholars, Trends in Stem Cells Biology and Technology offers a wide audience cutting edge information at a crucial time in this ever expanding field.
Clinical lung transplantation has seen an early start within the history of solid organ trans plantation, marked by the 1963 first lung transplant by James D. Hardy. This was prompted by the seemingly easy way of joining the transplanted organ to the recipient by me ans of a few well-defined anastomoses, i.e. bronchus, pulmonary artery and pulmonary vein carry ing left atrial cuff. The following decade thus witnessed a number of such mostly unilateral lung transplants in several centres, in Germany represented by the two only lung transplants performed by E. S. Bücherl, then at the Neukölln City Hospital in Berlin in 1969. As with most other such attempts these two patients suffered early ...