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RNA Splicing and Backsplicing: Disease and Therapy
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Frontal Lobe Seizures and Epilepsies in Children
A comprehensive international review of basic and clinical research based on the Mariani Foundation Colloquium on frontal lobe epilepsy in childhood and adolescence held at the Milan State University in October 2000. Distinguished authors discuss advances in neurogenetics, neuropsychology and imaging. This book describes clinical, electroencephalographic and neuroimaging patterns of frontal lobe epilepsy in detail and reviews advances in medical and surgical treatment. It will be useful and stimulating reading for pediatric and adult epilepsy specialists, psychiatrists, neuropsychologists and other behavioural scientists, and research workers in epileptology.
Postgraduate Haematology
The textbook of choice for trainees in haematology Over five editions Postgraduate Haematology has built a reputation as an extremely practical, user-friendly, reliable source of information for examination preparation and clinical practice. Completely revised to reflect the latest research in the field, this edition continues to provide trainees with up-to-date knowledge on the pathogenesis, clinical and laboratory features, and management of blood disorders. It covers the significant advances which have occurred in the application of cytogenetics and molecular genetics in the diagnosis, classification and understanding of haematological disorders. Coupled with the expertise of 34 new contr...
The Complicity of Friends
One of Victorian England’s most famous philosophers harbored a secret: Herbert Spencer suffered from an illness so laden with stigma that he feared its revelation would ruin him. He therefore went to extraordinary lengths to hide his malady from the public. Exceptionally, he drew two of his closest friends—the novelist George Eliot and her partner, G. H. Lewes—into his secret. Years later, he also shared it with a remarkable neurologist, John Hughlings-Jackson, better placed than anyone else in England to understand his illness. Spencer insisted that all three support him without betraying his condition to others—and two of them did so. But George Eliot, still smarting from Spencerâ€...
The Jews of Khazaria
The Jews of Khazaria chronicles the history of the Khazars, a people who, in the early Middle Ages, founded a large empire in eastern Europe (located in present-day Ukraine and Russia). The Khazars played a pivotal role in world history. Khazaria was one of the largest-sized political formations of its time, an economic and cultural superpower connected to several important trade routes. It was especially notable for its religious tolerance, and in the 9th century, a large portion of the royal family converted to Judaism. Many of the nobles and commoners did likewise shortly thereafter. After their conversion, the Khazars were ruled by a succession of Jewish kings that began to adopt the hal...
Epitranscriptomics: The Novel RNA Frontier
Following the formulation of the central dogma of molecular biology and the later discovery of classes of non-coding RNAs, the primary focus of Genetics was essentially on variation of DNA aiming at elucidating biological pathways perturbed in diseases. Recently, extensive attention has shifted towards the study of posttranscriptional RNA modifications occurring in both protein-coding as well as non-coding RNAs, revealing a novel and finer layer of complexity in gene regulation. This, in turn, has led to the birth of the novel field of ‘Epitranscriptomics’. The recent increase of applications of high-throughput sequencing technology (HTS) has allowed the unprecedented opportunity to iden...
Circulation
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