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Much of our knowledge of the cerebral circulation has been derived from studies of species other than human. There is increas ing recognition of species differences and concern that studies in animals may be misleading if unquestioningly applied to the human. A dramatic example of this occurred in the early his tory of the study of the circulation of the brain. Galen of Pergamo (131-201 AD) described a rete mirabile or "marvelous network" of blood vessels at the base of the human skull that he must have derived from observations of certain animals. This vascular structure was supplied by the carotid arteries which, after penetrating the cranium,"are divided into a large number of very small ...
The fundamental fault in hypertension is unknown. Calling it a fundamental fault, indeed, tacitly begs the question: Is there one fundamental fault, or are there several that are interlinked or interdependent? A simple yes or no answer cannot be offered. This volume is not designed to survey the up-to-date recent advances in research on hypertension, nor intended to provide provisional an swers to the so many unknowns in this topic. It is, in fact, an attempt to articulate questions that are worth asking, given the license of an unhibited, albeit disci plined, inquiry. The range of expression varies from dogmatic opinion to a declared speculation. Is the primary abnormality an excessive sodi...
Abstract: The current state of hypertension research is reviewed, focusing on 12 special hypertension concerns and covering each concern with the following: an evaluation of the current literature, recommendations for future research, and a comprehensive list of references. Volume 1, written for the public, examines hypertension as both a public health and a research problem, and Volume 2, written for the biomedical community, explores general recommendations, and summaries of scientific reports are covered in volumes 3 through 9.
Abstract: The current state of hypertension research is reviewed, focusing on 12 special hypertension concerns and covering each concern with the following: an evaluation of the current literature, recommendations for future research, and a comprehensive list of references. Volume 1, written for the public, examines hypertension as both a public health and a research problem, and Volume 2, written for the biomedical community, explores general recommendations, and summaries of scientific reports are covered in volumes 3 through 9.
Abstract: The current state of hypertension research is reviewed, focusing on 12 special hypertension concerns and covering each concern with the following: an evaluation of the current literature, recommendations for future research, and a comprehensive list of references. Volume 1, written for the public, examines hypertension as both a public health and a research problem, and Volume 2, written for the biomedical community, explores general recommendations, and summaries of scientific reports are covered in volumes 3 through 9.