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Los artículos compilados en el presente libro son un conjunto de miradas y reflexiones sobre el proceso de formación, son un conjunto de preguntas, experiencias compartidas, indagaciones y búsquedas, más que recetas o fórmulas sobre cómo enseñar.
Este libro está dirigido a quienes quieran mirar los diferentes modos en que se entrelazan los discursos, las prácticas y los sujetos en el campo de la intervención del Trabajo Social.
Las intervenciones de y desde el cuerpo, en Trabajo Social comienzan a emerger en el contexto neoliberal de fines de los años`90, cuando las estrategias de intervención que estructuraron tradicionalmente a la profesión del Trabajo Social (el informe, la entrevista, la denuncia) se volvieron estériles en la medida en que conceptualizaban a los sujetos de la intervención como agentes pasivos y victimizados. La emergencia de este tipo de intervenciones reactualizó el sentido del proyecto socio-político que caracterizó a ésta como una profesión al servicio de clases populares capaces de reflexionar críticamente, y de transformar, sus propias condiciones de vida. Estas prácticas resultan del estallido de los modos que asumieron las intervenciones en la versión institucionalizada del Trabajo Social. ¿El trabajo de y desde el cuerpo(s) como propuesta de intervención y herramienta política de autodeterminación puesta en acto, es lo suficientemente potente para aportar algo distinto e innovador a la disciplina del Trabajo Social contemporáneo? Pero... ¿De qué Trabajo Social hablamos? ¿Desde dónde, para quiénes y con qué?
This dictionary identifies more than 13,000 German-Jewish surnames from the area that was pre-World War I Germany. From Baden-Wuerttemburg in the south to Schleswig-Holstein in the north. From Westfalen in the west to East Prussia in the east. In addition to providing the etymology and variants of each name, it identifies where in the region the name appeared, identifying the town and time period. More than 300 sources were used to compile the book. A chapter provides the Jewish population in many towns in the 19th century.
This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different roles that cancer stem cells seem to have according to the organ they are placed in, and the future role that targeting cancer stem cells may have in the management of patients in the clinic. Exploring the latest research including new data from randomized trials, this book examines important proposals over the origin of cancer stem cells such as the possibility that cancer stem cells may arise fr...
This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.
This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.
Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily ...