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Cerebral vasospasm remains a major clinical problem in patients with subarachnoid hemorrhage. Neuroprotection with calcium antagonists, hemodynamic therapy and interventional angioplasty have an established role in the management of this disease, but an effective single drug for prevention or treatment of the vasospasm is still lacking. This book contains selected contributions to the 7th International Conference on Cerebral Vasospasm held in Interlaken, Switzerland, in June 2000. Part I of the book concentrates on basic science and experimental vasospasm. The molecular biology of vasospasm, the role of endothelin and nitric oxide as well as the potential of gene therapy are presented. Part ...
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The important issue of rehabilitation is usually not reflected in the neurosurgical literature but left to publications on neurological rehabilitation or neuropsychological literature. However, it is the neurosurgeon who should care for the functional rehabilitation of patients who are disabled by movement disorders, spasticity, epilepsy, pain, and disorders of the vegetative state as they suffer from acute or chronic central nervous system, spinal cord and peripheral nerve lesions. The papers in this volume highlight the state of the art, basic research, and clinical as well social-medical application of neurorehabilitation around the world, depending on different socio-cultural and economic situations as they were reported and discussed at recent international conferences and workshops of the World Federation of Neurosurgical Societies Committee on Neurorehabilitation and the Euroacademia Multidisciplinaria Neurotraumatologica.
Mit dem Sammelbegriff "undifferenzierte Astrozytome des GroBhirns" haben wir die supratentoriellen Astrozytome Grad III und IV nach Kerno han bezeichnet, die in der englischen Literatur als "high-grade supraten torial astrocytomas" zusammengefaBt werden. Wir haben diese Bezeich nung gewahlt, weil die Begriffe Glioblastom, malignes Astrozytom oder anaplastisches Astrozytom im deutschen Sprachgebrauch je nach verwen deter Nomenklatur eine spezifischere Bedeutung haben konnen. Die Erfolge mit randomisierten Studien und mit multimodaler Therapie bei anderen Malignomen und die EinfUhrung der Nitrosoharnstoffe in die Behandlung der Gliome an fangs der 70er Jahre haben das Interesse fUr die Therapi...
Arteriovenous malformations (AVM) and arteriovenous fistulas (AVF) differ from all other pathology affecting the central nervous system by their high-flow arteriovenous shunts. Permanent occlusion of these shunts is the essence and the challenge of therapy. Endovascular therapy and radiosurgery became accepted alternatives or adjuncts to surgery. In many instances the choice of the primary therapeutic modality is not clear and arguments can be found for several options. However, microsurgery, endovascular therapy and radiosurgery differ very much with regard to invasiveness, length of stay at the hospital but also residual risk after therapy. The emerging treatment concepts are the object of this book. The result is a unique structured presentation of AVM and AVF therapy.
Progess in specific computer-assisted techniques (digital imaging , computer-aided diagnosis, image-guided surgery, MEMS, etc.) combined with computer-assisted integration tools offers a valuable complement to or replacement for existing procedures in healthcare. Physicians are now employing PACS and telemedicine systems as enabling infrastructures to improve quality of and access to healthcare. Tools based on CAD and CAS facilitate completely new paths in patient care. To ensure that CARS tools benefit the patient, collaboration between various disciplines, specifically radiology, surgery, engineering, informatics, and healthcare management, is a critical factor. A multidisciplinary congress like CARS is a step in the desired direction of knowledge sharing and crossover education. It provides the necessary cooperative framework for advancing the development and application of modern computer-assisted technologies in healthcare.
Every few years a dissertation comes to the area of clinical application of medical technology which carries us forward as on a magic carpet into new regions of understanding and patient care. This book is such a magic carpet. It brings together, in a clear and incisive fashion, important hemodynamic principles with a simple noninvasive method of application to a part of the cerebral vasculature which has been relatively inaccessible. To the lucky and perceptive person who reads this book, a feeling of excitement and hope for progress is engendered. The diligent application of the potentials of transcranial Doppler ultrasound brings new power to our efforts in understanding the cerebral circ...