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Molecular Basis of Aging
Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:
Cell to Cell Signals in Plants and Animals
Summarizing research progress achieved in 32 areas of cell biology covered in this series, this volume places special emphasis on the following topics: recognition in parasitic and symbiotic systems - the molecular biology and genetics of susceptibility and resistance of plants and animals to pathogens, parasites and symbionts - the cell to cell recognition and differentiation - the most challenging problems in developmental biology of plants and animals - the plasticity in cell to cell communication which plays a major role in cell differentiation and function.
The Nramp Family
This book is the first comprehensive volume on the "Nramp family", highlighting the physiological importance of Nramp proteins as metal transporters. The molecular knowledge of these membrane proteins is presented from an evolutionary perspective, considering Nramp cellular function and mechanism of transport in key model organisms. The pathological significance of Nramp genetic polymorphism is discussed with emphasis on metal homeostasis and microbial infection. The chapters were contributed by leading investigators, providing a timely state of the art book in this rapidly growing field. The Nramp Family will be useful to a broad community of scientists interested in metal transport and molecular biology. It will be of interest to the research audience in the broad fields of metal ions and molecular medicine.
Towards Evolvable Hardware
Evolutionary computing, inspired by the biological world, is one of the emergent technologies of our time. Being essentially a software activity, it has been successfully applied, e.g. for optimization and machine learning in various areas. The tremendous increase in computational power and, more recently, the appearance of a new generation of programmable logic devices allow for a new approach to designing computing machines inspired by biological models: it is now possible to make the hardware itself evolve. This book is based on a workshop on evolvable hardware, held in Lausanne, Switzerland, in October 1995. It reports the state of the art of research in this field and presents two introductory chapters, written with the novice reader in mind.
Women’s Health and Menopause
The 4th International Symposium on Women's Health and Menopause, organized by the Giovanni Lorenzini Medical Foundation (Milan, Italy and Houston, Texas) focused on the new strategies to improve the quality of life of post-menopausal women. This volume illustrates the findings of this conference and includes information on the age-related degenerative processes occurring after menopause including cardiovascular disease, cancer, fractures and dementia.
Cellular and Molecular Methods in Neuroscience Research
There are numerous books on cellular and molecular protocols for general use in cell biology but very few are exclusively devoted to neurobiology. This book fills this gap and explains in a clear and consistent manner, some of the more commonly used protocols in neuroscience research. Each chapter is written by either the person who invented the procedure or an expert in the field. The format is uniform: "Overview," "Background," "Protocols," and "results and discussion." Each protocol begins with the principle of the technique, studies in cell culture, materials and reagents, and, lastly, step-by-step outline of the procedure itself. This highly practical book is also well illustrated (with 17 four color plates) to make the concepts and procedures easy to understand and perform.
A Pan-Chromatic View of Clusters of Galaxies and the Large-Scale Structure
The reviews presented in this volume cover a huge range of cluster of galaxies topics. Readers will find the book essential reading on subjects such as the physics of the ICM gas, the internal cluster dynamics, and the detection of clusters using different observational techniques. The expert chapter authors also cover the huge advances being made in analytical or numerical modeling of clusters, weak and strong lensing effects, and the large scale structure as traced by clusters.
Offshore Geotechnical Engineering
Design practice in offshore geotechnical engineering has grown out of onshore practice, but the two application areas have tended to diverge over the last thirty years, driven partly by the scale of the foundation and anchoring elements used offshore, and partly by fundamental differences in construction and installation techniques. As a consequence offshore geotechnical engineering has grown as a speciality. The structure of Offshore Geotechnical Engineering follows a pattern that mimics the flow of a typical offshore project. In the early chapters it provides a brief overview of the marine environment, offshore site investigation techniques and interpretation of soil behaviour. It proceeds to cover geotechnical design of piled foundations, shallow foundations and anchoring systems. Three topics are then covered which require a more multi-disciplinary approach: the design of mobile drilling rigs, pipelines and geohazards. This book serves as a framework for undergraduate and postgraduate courses, and will appeal to professional engineers specialising in the offshore industry.
