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Working on the Bomb
The history of the Hanford Engineering Works, a site in eastern Washington that produced and separated plutonium for the Manhattan Project.
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Immunotherapy for Pediatric Malignancies
This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed, with particular focus on their potential application to pediatric cancers. Practical aspects of delivering such therapies to children, likely toxicities and potential biomarkers are considered. Finally, consideration is given to how, in the longer term, such therapies may be combined with conventional therapies such as chemotherapy and radiotherapy. Edited by two distinguished pediatric oncologists with a collection of chapters from the most authoritative experts in cancer immunotherapy, this is an indispensable volume for pediatric oncologists and physicians working in childhood cancer care.
The Atomic West
The Manhattan Project—the World War II race to produce an atomic bomb—transformed the entire country in myriad ways, but it did not affect each region equally. Acting on an enduring perception of the American West as an “empty” place, the U.S. government located a disproportionate number of nuclear facilities—particularly the ones most likely to spread pollution—in western states. The Manhattan Project manufactured plutonium at Hanford, Washington; designed and assembled bombs at Los Alamos, New Mexico; and detonated the world’s first atomic bomb at Alamagordo, New Mexico, on June 16, 1945. In the years that followed the war, the U.S. Atomic Energy Commission selected additiona...
When the Spirit Says Sing!
In the late 1950s and early 1960s, such songs as "We Shall Overcome," "Keep Your Eyes on the Prize," and "Do What the Spirit Says Do" were sung at virtually every mass meeting, demonstration, and planning session of Civil Rights activists. They were sung on the Freedom Rides, during the marches, and in jail cells of the South. Movement activists have commented frequently and eloquently on the ways that singing and songs gave them strength and a sense of self. This study offers a close analysis of the lyrics of the songs most central to the Civil Rights Movement, with an eye to understanding the songs as self-persuasion. In the songs, the activists defined themselves and their world, and reinforced a plan of action for their participation in the Movement. This analysis of the freedom songs is set in the context of Movement history and supported with commentary from activists and background information on Movement activities. In addition, this study offers readers insights into the moving and inspiring power of the freedom songs.
