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Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders
Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.
Interrogation and Torture
This book develops, for the first time, a comprehensive discussion regarding the legality of torture and the efficacy of interrogation. Scientific research has concluded that torture is not effective. So, what interrogational methods are effective and how does one deploy those methods in such a way that is consistent with law and morality?
The Brain's Sense of Movement
This interpretation of perception and action allows Alain Berthoz to focus on psychological phenomena: proprioception and kinaesthesis; the mechanisms that maintain balance and co-ordination actions; and basic perceptual and memory processes involved in navigation.
Official Register
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Motor Learning and Synaptic Plasticity in the Cerebellum
This book is concerned with the involvement of the cerebellum in learning and remembering motor tasks. It is unique in discussing plasticity at both the cellular and at the behavioral level.
In Praise of Walking
'Informative and persuasive enough to rouse the most ardent couch pototo' New Scientist Walking upright on two feet is a uniquely human skill. It defines us as a species. It enabled us to walk out of Africa and to spread as far as Alaska and Australia. It freed our hands and freed our minds. We put one foot in front of the other without thinking - yet how many of us know how we do that, or appreciate the advantages it gives us? In this hymn to walking, neuroscientist Shane O'Mara invites us to marvel at the benefits it confers on our bodies and minds, and urges us to appreciate - and exercise - our miraculous ability. Take this mindful approach to walking into the new year. 'Will leave you itching to go out for a good old-fashioned stroll' Mail on Sunday *A Sunday Independent Book of the Week*
Alzheimer's Disease
Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.
Shadow of a Taxman
Who funded the Irish Revolution? In Shadow of a Taxman, R. J. C. Adams investigates how the unrecognised Irish Republic's money was solicited, collected, transmitted, and safeguarded, as well as who the financial backers were and what influenced their decision to contribute from as far afield as New York, Buenos Aires, Cape Town, and Melbourne.
