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T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases
This book presents the state of the art in cellular and molecular mechanisms regulating the immune response in allergic inflammation. Special attention is given to the central role of regulatory T cells (Treg) in immune regulation and induction of peripheral tolerance, as well as to the relevance of Th17 cells in chronic inflammation. The importance of Treg and Th17 cells is demonstrated in bronchial asthma, atopic eczema, contact dermatitis and delayed-type hypersensitivity. Furthermore, T-cell-mediated regulatory mechanisms in helminthic infections and fungal allergy are discussed. Several chapters are devoted to the therapeutic consequences that these recently discovered T-cell functions ...
Connexins
Connexins: A Guide is a practical and valuable reference and text covering a wide scope of information about the connexin family of membrane channel proteins. The editors and contributing authors intend for this cutting-edge work to be informative to scientists wishing to learn about the field, as well as to those who are active researchers in this area. Connexins: A Guide masterfully addresses specific needs of the scientific community; it is a comprehensive and comprehensible narrative of the uncommonly diverse connexin field, making previously hard-to-find information easily accessible, while also presenting intelligible insights into the extensive experimental methods and conceptual frameworks necessary to appreciate and understand the important roles that connexin channel proteins play in health and disease.
Failures of American Civil Justice in International Perspective
Civil justice in the United States is neither civil nor just. Instead it embodies a maxim that the American legal system is a paragon of legal process which assures its citizens a fair and equal treatment under the law. Long have critics recognized the system's failings while offering abundant criticism but few solutions. This book provides a comparative-critical introduction to civil justice systems in the United States, Germany and Korea. It shows the shortcomings of the American system and compares them with German and Korean successes in implementing the rule of law. The author argues that these shortcomings could easily be fixed if the American legal systems were open to seeing how other legal systems' civil justice processes handle cases more efficiently and fairly. Far from being a treatise for specialists, this book is an introductory text for civil justice in the three aforementioned legal systems.
Failures of American Methods of Lawmaking in Historical and Comparative Perspectives
In this book, James R. Maxeiner takes on the challenge of demonstrating that historically American law makers did consider a statutory methodology as part of formulating laws. In the nineteenth century, when the people wanted laws they could understand, lawyers inflicted judge-made, statute-destroying, common law on them. Maxeiner offers the cure for common law, in the form of sensible statute law. Building on this historical evidence, Maxeiner shows how rule-making in civil law jurisdictions in other countries makes for a far more equitable legal system. Sensible statute laws fit together: one statute governs, as opposed to several laws that even lawyers have trouble disentangling. In a statute law system, lawmakers make laws for the common good in sensible procedures, and judges apply sensible laws and do not make them. This book shows how such a system works in Germany and would be a solution for the American legal system as well.
Gap Junctions in the Brain
In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hôpital Charles Foix, Centre de Recherche et Développement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).
Current List of Medical Literature
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
Single Membrane Channels Formed by Connexins or Pannexins: Focus on the Nervous System
Given that the extremely elaborated and dynamic functions performed by the nervous system require the close synchronization of brain cells, complex organisms have developed different mechanisms of intercellular communication. At this regard, paracrine signaling between neighboring cells is currently recognized as one of the most widely distributed mechanisms of synchronization in the brain parenchyma. In mammals, paracrine signaling is in part mediated by single membrane channels formed by connexins (connexons/hemichannels) or pannexins (pannexons), which are two different membrane protein families composed of about 20 and 3 members, respectively. Single membrane channels formed by these pro...
Asthma and COPD
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
