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Written by nearly 60 of the world's leading investigators in this rapidly expanding field, this state-of-the-art reference furnishes detailed presentations on the basic science and clinical aspects of cilia, mucus, and mucociliary interactions. Providing stimulating coverage of the latest information in a single source, Cilia, Mucus, and Mucociliary Interactions discusses the genetic determinants of mucociliary system structure and function explains ciliary wave activity in cell-cell communication elucidates many of the key physiological processes in ciliary regulation reveals possible means of treating irregularities in mucus secretion and clearance improves understanding of clinical syndro...
This book examines the evolution of counter-terrorism (CT) policies in liberal democracies since 2001, with a specific focus on the case of Belgium. What is counter-terrorism (CT)? While the answer to this question may seem self-evident, it has become quite complicated to define the contours of a field that has expanded dramatically in the two decades since the 9/11 attacks. The development of "softer" policies, dealing with the prevention of radicalisation, has blurred the limits of CT. Through the use of public policy theory and an in-depth case study on Belgium, the book identifies the key factors influencing CT policy-making, both domestically and internationally, and offers an explanation for the development of a more comprehensive CT agenda across Europe. It provides an innovative theoretical approach and is also based on extensive interviews with key counter-terrorism officials and analysis of key policy documents. The book concludes by identifying some key drivers of change and offers an embryonic theory of CT policy-making. The book will be of much interest to students and practitioners of counter-terrorism, radicalisation, European politics and security studies.
Allergy and Allergic Diseases has been organized to provide an up-to-date, clinically relevant compilation of one of the most exciting areas of investigation in medicine today-allergic disease, especially as it pertains to the skin, airways, and bowel. With the dramatic rise in the incidence of various allergic disorders worldwide, and the coming of age of the discipline of Clinical Immunology and Allergy, the interface between basic and clinical science in this arena demands highlighting in this comprehensive new syn thesis.1t is with the hope of filling this evident need that Allergy and Allergic Diseases: The New Mechanisms and Therapeutics has been put together. The book's content is div...
Peter Gunnarson Rambo, son of Gunnar Petersson, was born in about 1612 in Hisingen, Sweden. He came to America in 1640 and settled in Christiana, New Sweden (now Delaware). He married Brita Mattsdotter 7 April 1647. They had eight children. He died in 1698. HIs daughter, Gertrude Rambo, was born 19 October 1650. She married Anders Bengtsson. Descendants and relatives lived mainly in Pennsylvania, Delaware, Virginia, North Carolina and Ohio.
This comprehensive new book, Agricultural Health and Safety, provides extensive coverage of issues arising in the interrelated fields of health, agriculture, and the environment. The significance of this book is a direct result of the increasing number of health and safety issues in agriculture and its associated industries. It contains sections written by experts, and includes papers presented at the Third International Symposium for Issues in Health, Agriculture and the Environment. Topics include lung disease in farmers, respiratory effects of long-term exposure to grain dust and air contaminants, respiratory hazards of pork producers, occupational asthma, allergic disorders in plant growers, allergic rhinitis in farmers, respiratory effects of inhaled endotoxins, organic dust toxic syndrome, cancer risks, hazards of pesticides, neurological risks, work-related accidents, prevention and safe practice, sustainable farming systems, and more. In all cases, the issues are broadly integrated with those of the environment. No other book presents such a broad perspective of the field.
Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain. - Neurogenic inflammation in historical perspective - Cardiac protection by nociceptive afferents - Molecular mechanisms of nociception - Sensory mechanisms in migraine pathophysiology - Vagal signaling of visceral inflammation - Neurogenic mechanisms in arthritis - Therapeutic implications of vanilloid-type compounds
Muscarinic acetylcholine receptors have played a key role in the advancement of knowledge of pharmacology and neurotransmission since the inception of studies in these fields, and the effects of naturally occurring drugs acting on muscarinic receptors were known and exploited for both therapeutic and non-therapeutic purposes for hundreds of years before the existence of the receptors themselves was recognized. This volume presents a broad yet detailed review of current knowledge of muscarinic receptors that will be valuable both to long-time muscarinic investigators and to those new to the field. It describes the detailed insights that have been obtained on the structure, function, and cell biology of muscarinic receptors. This volume also describes physiological analyses of muscarinic receptors and their roles in regulating the function of the brain and of a variety of peripheral tissues. This volume shows how the study of muscarinic receptors continues to provide new and surprising insights not just to the cholinergic system but to the broad areas of neurobiology, cell biology, pharmacology, and therapeutics.
This work sets out to provide the information necessary for understanding endotoxin and its effects on the lungs, and explicates the difficulties in determining how to manipulate endotoxin pathobiology. The rationale for, and efficacy of, current and experimental treatments for sepsis, adult respiratory distress syndrome and other endotoxin-induced lung injuries are discussed.
The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.