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DNA Polymerases
  • Language: en
  • Pages: 338

DNA Polymerases

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.

Cumulated Index Medicus
  • Language: en
  • Pages: 800

Cumulated Index Medicus

  • Type: Book
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  • Published: 1978
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  • Publisher: Unknown

None

Links Between Recombination and Replication
  • Language: en
  • Pages: 303

Links Between Recombination and Replication

There has been a sea change in how we view genetic recombination. When germ cells are produced in higher organisms, genetic recombination assures the proper segregation of like chromosomes. In the course of that process, called meiosis, recombination not only assures segregation of one chromosome of each type to progeny germ cells, but also further shuffles the genetic deck, contributing to the unique inheritance of individuals. In a nutshell, that is the classical view of recombination. We have also known for many years that in bacteria recombination plays a role in horizontal gene transfer and in replication itself, the latter by establishing some of the replication forks that are the stru...

DNA Damage Recognition
  • Language: en
  • Pages: 871

DNA Damage Recognition

  • Type: Book
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  • Published: 2005-09-19
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  • Publisher: CRC Press

Stands as the most comprehensive guide to the subject-covering every essential topic related to DNA damage identification and repair. Covering a wide array of topics from bacteria to human cells, this book summarizes recent developments in DNA damage repair and recognition while providing timely reviews on the molecular mechanisms employe

DNA Repair and Cancer
  • Language: en
  • Pages: 720

DNA Repair and Cancer

  • Type: Book
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  • Published: 2013-01-22
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  • Publisher: CRC Press

DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.

DNA Repair and Mutagenesis
  • Language: en
  • Pages: 2587

DNA Repair and Mutagenesis

An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage are detailed. • Provides information on covering sources and consequences of DNA damage; correcting altered bases in DNA: DNA repair; DNA damage tolerance and mutagenesis; regulatory responses to DNA damage in eukaryotes; and disease states associated with defective biological responses to DNA damage.

Ultrasonics
  • Language: en
  • Pages: 904

Ultrasonics

  • Type: Book
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  • Published: 2024-02-21
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  • Publisher: CRC Press

Updated, revised, and restructured to reflect the latest advances in science and applications, the fourth edition of this best-selling industry and research reference covers the fundamental physical acoustics of ultrasonics and transducers, with a focus on piezoelectric and magnetostrictive modalities. It then discusses the full breadth of ultrasonics applications involving low power (sensing) and high power (processing) for research, industrial, and medical use. This book includes new content covering computer modeling used for acoustic and elastic wave phenomena, including scattering, mode conversion, transmission through layered media, Rayleigh and Lamb waves and flexural plates, modern h...

DNA Photodamage
  • Language: en
  • Pages: 361

DNA Photodamage

Written in an accessible and comprehensive manner, DNA Photodamage will appeal to all scientists working in the area whether specialists in the discipline or not and provides a complete coverage of the field, from ultrafast spectroscopy to biomedical research.

Biology and Breeding of Crucifers
  • Language: en
  • Pages: 568

Biology and Breeding of Crucifers

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

Considerable interest has developed in recent years in crucifers and particularly in their wild relatives, as they contain genetic material that may be utilized for further evolution of superior crop varieties through introgression and distant hybridization. Until now, there has been no single volume that focuses exclusively on the biology and bree

Plant Breeding Reviews
  • Language: en
  • Pages: 432

Plant Breeding Reviews

Plant Breeding Reviews presents state-of-the-art reviews on plant breeding and genetics covering horticultural, agronomic and forestry crops, incorporating both traditional and molecular methods. The contributions are authored by world authorities, anonymously reviewed, and edited by Professor Jules Janick of Purdue University, USA. The series is an indispensible resource for crop breeders, plant scientists, and teachers involved in crop improvement and genetic resources. Initiated in 1983, Plant Breeding Reviews is published in the form of one or two volumes per year. Recently published articles include: Epigenetics and Plant Breeding (v30) Enhancing Crop Gene Pools with Beneficial Traits Using Wild Relatives (v30) Coffee Germplasm Resources, Genomics and Breeding (v30) Molecular Genetics and Breeding for Fatty Acid Manipulation in Soybean (v30) Breeding Southern Highbush Blueberries (v30) Development of Fire Blight Resistance by Recombinant DNA Technology (v29)