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This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss: Challenges of Identifying Mycobacterium to the Species level Identification of Bacteroides and Other Clinically Relevant Anaerobes Identification of Species in Mixed Microbial Populations Detection of Resistance Mechanisms Proteomics as a biomarker discovery and validation platform Determination of Antimicrobial Resistance using Tandem Mass Spectrometry
Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry Detailed resource presenting the capabilities of MALDI mass spectrometry (MS) to industrially and environmentally significant areas in the biosciences Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry fulfills a need to bring the key analytical technique of MALDI mass spectrometric analysis into routine practice by specialists and non-specialists, and technicians. It informs and educates established researchers on the development of techniques as applied to industrially significant areas within the biosciences. Throughout the text, the reader is presented with recognized and emerging techniq...
New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections that follow the general progression in which most microbiology laboratories are approaching the subject –Transition, Tools, Preparation, Profiling by Patterns, Target Proteins, and Data Analysis.
Includes a revised taxonomic outline for the phyla Bacteroidetes, Planctomycetes, Chlamydiae, Spirochetes, Fibrobacteres, Fusobacteria, Acidobacteria, Verrucomicrobia, Dictyoglomi, and Gemmatimonadetes based upon the SILVA project as well as a description of more than 153 genera in 29 families. Includes many medically important taxa.
Methods in microbial systematics have developed and changed significantly in the last 40 years. This has resulted in considerable change in both the defining microbial species and the methods required to make reliable identifications. Developments in information technology have enabled ready access to vast amounts of new and historic data online. Establishing both the relevance, and the most appropriate use, of this data is now a major consideration when undertaking identifications and systematic research. This book provides some insights into how current methods and resources are being used in microbial systematics, together with some thoughts and suggestions as to how both methodologies and concepts may develop in the future.
Contains abstracts of papers presented at meeting of the Society for General Microbiology.
Includes information on infection detection and prevention and control, diagnostic technologies, bacteriology, antibacterial, antiviral, antifungal, and antiparasitic agents and susceptibility test methods, virology, mycology, and parasitology.
Includes information on infection detection and prevention and control, diagnostic technologies, bacteriology, antibacterial, antiviral, antifungal, and antiparasitic agents and susceptibility test methods, virology, mycology, and parasitology.