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Metabolic Reprogramming
This volume provides state-of-the-art methods and protocols from researchers in the field of metabolism. Chapters guide readers through methodologies measuring different aspects of lipid metabolism, quantifying the amino acids, mitochondrial and intracellular by-products, detect enzyme and kinase activities, detecting a variety of metabolic pathways, and intracellular networks including nucleotide metabolism and the metabolic response to hypoxia and cytotoxic drugs. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Metabolic Reprogramming: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
The Warburg Effect Regulation Under Siege: The Intertwined Pathways in Health and Disease
Many cells, including immune, neuronal, cancer and stem cells, become dependent on aerobic glycolysis to escape apoptosis and accommodate their bioenergetics needs. How this metabolic change, also known as the Warburg effect, is regulated remains largely unknown. The Warburg effect has been widely investigated in cancer cells where it was first observed with the aim of decoding the molecular networks controlling its activation for therapeutic purposes. This Research Topic aimed to discuss and review all the intracellular signaling regulating the Warburg effect in cancerous and normal non-cancerous cells though original research articles, mini reviews and reviews.
Parliamentary Papers
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Queen Of Killers
He took everything from me, now it's my turn and what my husband isn't expecting, is that I play on BLOOD I was his second choice, his biggest mistake. I never wanted things to turn out the way they did, but they did. Now my choice is limited. Join him, or end him. What will I choose? The clock is ticking, my friend's life is hanging on a thread and I, Aliyana Capello am the only one who can save him. But at what cost? I love my husband, but sometimes love is not enough, sometimes there are more important moves that need to be made. It is unfortunate that some would need to fall so I, the Queen of Killers can take my place and lead them all. Once all is done, I will need to confess. So I am going to start by saying forgive me. The final part of Secrets of the Famiglia, tells all. This is an enemy to lovers book, read at your own risk, no promises of a happy ending, but I guarantee you, this story will blow your mind.
Neuroprotection Methods and Protocols
This book examines current research into the role of neuronal death in cell signaling pathways, and its role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. After introducing neurodegenerative, traumatic, and ishemic disorders, the authors cover in vitro and animal systems, and cellular and molecular mechanisms.
The Reel Middle Ages
Those tales of old--King Arthur, Robin Hood, The Crusades, Marco Polo, Joan of Arc--have been told and retold, and the tradition of their telling has been gloriously upheld by filmmaking from its very inception. From the earliest of Georges Melies's films in 1897, to a 1996 animated Hunchback of Notre Dame, film has offered not just fantasy but exploration of these roles so vital to the modern psyche. St. Joan has undergone the transition from peasant girl to self-assured saint, and Camelot has transcended the soundstage to evoke the Kennedys in the White House. Here is the first comprehensive survey of more than 900 cinematic depictions of the European Middle Ages--date of production, country of origin, director, production company, cast, and a synopsis and commentary. A bibliography, index, and over 100 stills complete this remarkable work.
Dante Alighieri
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Divine Comedy
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Movie Roadshows
This work examines a film distribution system paralleling the rise of early features and persisting until 1972, when Man of La Mancha was the final roadshow to require reserved seating. Synonymous with Hollywood's star-studded premieres, roadshows were longer and cost more than regular features, making the experience similar to attending the legitimate theater. Roadshows, often epic in subject matter, played selected (usually only one) theaters in major urban centers until demand decreased. De rigueur by the 1960s were musical overtures, intermissions, entre'acte and exit music and souvenir programs for sale in the lobby. Throughout the text are recollections by people who attended roadshows, including actor John Kerr and actresses Barbara Eden and Ingrid Pitt. The focus is on roadshows released in the United States but an appendix identifies international roadshows and films forecast but not released as roadshows. Included are plots, contemporary critical reaction, premiere dates, production background, and methods of promotion--i.e., the ballyhoo.
