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Esta obra reúne sete capítulos elaborados e apresentados por estudantes do curso de Licenciatura em Química da Universidade Tecnológica Federal do Paraná, campus Campo Mourão, no âmbito das disciplinas Didática Geral e Química Orgânica Teórica 2 entre os anos de 2015 e 2019. Cada capítulo contempla um plano de aula ou de unidade referente aos conteúdos trabalhados na disciplina de Química do ensino médio. A despeito da diversidade de conteúdos e temas abordados, todos os capítulos deste material têm o mesmo objetivo: oferecer aos estudantes de Licenciatura em Química e professores – e a quem mais possa interessar – mais um material de estudos ou recurso didático que possa ser utilizado para o ensino de Química na educação básica.
This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
Anxiety disorders are amongst the most common of all mental health problems. Research in this field has exploded over recent years, yielding a wealth of new information in domains ranging from neurobiology to cultural anthropology to evidence-based treatment of specific disorders. This book offers a variety of perspectives on new developments and important controversies relevant to the theory, research, and clinical treatment of this class of disorders. Clinicians will find reviews of state-of-the-art treatments for panic disorder, social anxiety disorder, phobias, obsessive-compulsive disorder, generalized anxiety disorder, and post-traumatic stress disorder, as well as controversies over diagnostic and treatment issues. Researchers will find in-depth consideration of important selected topics, including genetics, neuroimaging, animal models, contemporary psychoanalytic theory, and the impact of stressors. This book illustrates the enormous advances that have occurred in anxiety research and describes the evolving multi-disciplinary efforts that will shape the future of the field.
AS THE WORLD BURNS, ONLY A DREAMER CAN SAVE IT New York, 2000. The United Nations has just planted its flag on Mars, and a Green Party senator is about to become the first female president of the United States. At a party in the almost-Utopian world, Kate and Ben fall in love. London, 1593. Kate wakes as Emilia, mistress to a nobleman and friend to a lowly court poet called Will. Afflicted by apocalyptic premonitions, she sets out to save the world. Each decision she makes as Emilia will change Kate's life with Ben forever.
* RITA finalist for Best Historical Romance * USA Today bestseller A Marriage of Convenience... Gaunt and wearing an eye patch, Major Ian Cameron returns to India after being freed from horrendous captivity in Central Asia. Thoughts of his beautiful fiancée helped him survive his imprisonment, but much can happen when a man has supposedly been dead for two years, and his return brings him face to face with how much he has lost. An unexpected inheritance gives him the opportunity to return home to Scotland and begin a new life. First, though, he must fulfill the dying wish of the Russian officer who had shared his captivity by delivering the colonel’s journal to his niece, Larissa Alexandr...
Sharing stories of myths, legends and ancient bogs, a deaf child and her grandmother experiment with the lyrical beauty of sign language. Learning to communicate through their shared love of trees they find solace in the shapes and susurrations of leaves in the wind. A poignant tale of family bonding and the quiet acceptance of change. What Willow Says was the winner of the Barbellion Prize 2021
This FIFA endorsed book gives the first formal scientific consensus on players’ energy use, fluid and nutritional requirements. With new research, this book has an applied focus, developed with input from sports nutrition club professionals.
The original new age nudist movement in Switzerland.