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Signal Analysis in Pharmacovigilance
This book provides detailed concepts and information on principles and processes of signal analysis in pharmacovigilance along with case studies. It covers the fundamental concepts and principles of pharmacovigilance, emphasizing the need for robust signal detection and analysis methods. The book reviews the diverse array of databases and tools employed for signal detection, including electronic health records (EHRs), social media mining, claims data, and distributed data networks. In turn, the book discusses the application of molecular dynamics, molecular docking, and the use of the FDA Adverse Event Reporting System (FAERS) database in signal analysis. Toward the end, the book explores the identification, validation, and assessment of signals associated with vaccines. This book is useful for graduate, post-graduate students of pharmaceutical sciences, and scientists in pharmacology research and drug development.
A Review on Diverse Neurological Disorders
According to World Health Organization (WHO) one billion people worldwide are affected by one of the thousands of neurological disorders, including epilepsy, Alzheimer disease, strokes, and headaches. Neurological disorders also include brain injuries, neuroinfections, multiple sclerosis and Parkinson disease. A Review on Neurological Disorders: Pathophysiology, Molecular Mechanisms, and Therapeutics covers the major topics related to neurological disorders, current challenges in diagnosis and intervention. This book is organized into four distinct sections, starting with an introduction, providing a general overview of the epidemiology of neurological disorders, pathogenesis and management....
Health Happiness Harmony
Do you agree that health is the greatest wealth? But what do we aspire to achieve most of the time? Material wealth. Very often this aspiration leads to wrong lifestyle choices, resulting in all sorts of imbalances - mental, emotional, physical, environmental, and social, and along the way, one forgets the greatest wealth i. e. HEALTH. This imbalance is the cause of stress, worries, unhappiness, depression and much more. But the good news is, we can regain and reclaim the life balances by adopting Yoga as a lifestyle choice. This book is about raising awareness on how Yoga can be a great lifestyle choice to regain life’s balances. It helps in every age and every stage of one’s life, for a healthy person to maintain positive health or for someone suffering from lifestyle related disorders or to improve presence and productivity in corporates. It is a great companion to a woman in every stage of her life and the problems it brings. Yoga can be a great maintenance strategy for anyone to maintain and manage health after 40. Yoga will help instil the balance of mind, body, and soul to achieve abundance of Health, Harmony, and Happiness in everyone's life.
Global Perspectives on Precision Medicine
This book presents the promises of Precision Medicine (PM) and the challenges of its implementation in daily clinical routine, while addressing the anticipated ethical and social implications. It is the first book that critically analyzes the potential and the dilemmas relevant to genomics and precision medicine from healthcare, public health and global perspectives. The nine chapters presented in this book elaborate on pharmacogenomics' crucial role in maximizing the potential benefits and minimizing medication's potential risks in groups of people, especially in cancer treatment and other health conditions. Infectious and non-communicable diseases (NCDs) are also discussed in this book by identifying challenges and ways to overcome them. Essential concepts are addressed, such as health-related benefits and harm to individuals and the broader community, including threats to individual privacy and autonomy, which warrant just distribution of scarce resources. The book also identifies and addresses the lack of competency in the healthcare workforce in the era of PM and discusses the path to laying the ethical foundation for the implementation of PM in healthcare organizations.
Pluriversal Conversations on Transnational Feminisms
This edited volume brings transnational feminisms in conversation with intersectional and decolonial approaches. The conversation is pluriversal; it voices and reflects upon a plurality of geo- and corpopolitical as well as epistemic locations in specific Global South/East/North/West contexts. The aim is to explore analytical modes that encourage transgressing methodological nationalisms which sustain unequal global power relations and which are still ingrained in the disciplinary perspectives that define much social science and humanities research. A main focus of the volume is methodological. It asks how an engagement with transnational, intersectional, and decolonial feminisms can stimula...
Pharmaceutical Policy in Countries with Developing Healthcare Systems
A comprehensive and granular insight into the challenges of promoting rational medicine, this book serves as an essential resource for health policy makers and researchers interested in national medicines policies. Country-specific chapters have a common format, beginning with an overview of the health system and regulatory and policy environments, before discussing the difficulties in maintaining a medicines supply system, challenges in ensuring access to affordable medicines and issues impacting on rational medicine use. Numerous case studies are also used to highlight key issues and each chapter concludes with country-specific solutions to the issues raised. Written by highly regarded academics, the book includes countries in Africa, Asia, Europe, the Middle East and South America.
Advances in Cancer Biomarkers Research
Advances in Cancer Biomarkers Research provides a thorough and detailed description of cancer biomarkers for diagnostic, prognostic and therapeutics in several cancer types. The book presents a compendium of topics related to current advanced research, along with fundamental knowledge that will help readers fully comprehend the field of cancer biomarkers. Topics discussed include such the role of genetic mechanisms, epigenetics, DNA and microRNA in different cancers, signaling pathways and exosomes. In addition, the book discusses biomarker research applied to several cancer types, such as head and neck, urological, lung, bone tumors, hematological and neurological malignancies and breast ca...
