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A Certain Exposure
Satirical and sympathetic, political and personal, A Certain Exposure traces the adolescences of twin brothers Andrew and Brian, culminating in the explosive events leading to Andrew’s tragic death. This is a classic coming-of-age tale doubled across two vividly individual brothers, who struggle to navigate a complex tangle of relationships and coercive forces, cinematically interwoven with the yearnings and fears of an ensemble of mothers, fathers, cousins, friends and lovers both false and true. This wide-ranging debut beautifully presents the resonances and the ghosts of lost possibilities, as well as a gripping story of hope and betrayal.
Identification of novel modulators towards high cell density and high-producing Chinese hamster ovary suspension cell cultures as well as their application in biopharmaceutical protein production
Amongst the mammalian producer cell lines, the Chinese hamster ovary (CHO) cell lines are of predominant importance in biopharmaceutical production. Thus, novel factors increasing overall productivity are sought and bear the potential to reduce the unit costs of a production process. Furthermore, the current patent situation for several therapeutic proteins demands innovative tools to at least maintain or preferentially increase the cost-effectiveness of their production processes. In this thesis, hitherto unknown factors were revealed by next generation sequencing of chemically mutated and selected CHO-K1 suspension cell lines. Two factors were proven to improve CHO-based production process...
Open Source Development, Communities and Quality
We are very pleased to introduce Open Source Development, Communities and Quality. The International Conference on Open Source Systems has come to its fourth edition – OSS 2008. Now, Free, Libre, and Open Source software is by all means now one of the most relevant subjects of study in several disciplines, ranging from information technology to social sciences and including also law, business, and political sciences. There are several conference tracks devoted to open source software with several publications appearing in high quality journals and magazines. OSS 2008 has been organized with the purpose of being the reference venue for those working in this area, being the most prominent conference in this area. For this th reason OSS 2008 has been located within the frameworks of the 20 World Computer Congress, WCC 2008, in Milan, the largest event of IFIP in 2008. We believe that this conference series, and the IFIP working group it represents, can play an important role in meeting these challenges, and hope that this book will become a valuable contribution to the open source body of research.
