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Mitochondria and Endoplasmic Reticulum Dysfunction in Parkinson’s Disease
Several pathogenic mechanisms are involved in the pathogenesis of Parkinson’s Disease (PD), a neurodegenerative disease characterized by the loss of substantial nigra (SN) dopamine (DA) neurons. Alterations in calcium (Ca2+) homeostasis, cellular proteostasis, axonal transport, mitochondrial function, and neuroinflammation are linked to PD. However, research involving inter-organelle communication and their significance as precise mechanisms underlying neuronal death in PD remain to be elucidated. Evidence showed that perturbations in the mitochondria-endoplasmic reticulum (ER) network play an important role in the pathogenesis of PD. Alterations in the mitochondria-ER interface have been ...
Mitochondria and Endoplasmic Reticulum Dysfunction in Parkinson's Disease
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Pattern Recognition in Bioinformatics
This book constitutes the refereed proceedings of the International Workshop on Pattern Recognition in Bioinformatics, PRIB 2007, held in Singapore in October 2007. The 38 revised full papers presented were carefully reviewed and selected from 125 submissions. The papers discuss the applications of pattern recognition methods in the field of bioinformatics to solve problems in life sciences.
Proceedings of Integrated Intelligence Enable Networks and Computing
This book presents best selected research papers presented at the First International Conference on Integrated Intelligence Enable Networks and Computing (IIENC 2020), held from May 25 to May 27, 2020, at the Institute of Technology, Gopeshwar, India (Government Institute of Uttarakhand Government and affiliated to Uttarakhand Technical University). The book includes papers in the field of intelligent computing. The book covers the areas of machine learning and robotics, signal processing and Internet of things, big data and renewable energy sources.
Environmental Nanotechnology
This is the second volume on Environmental Nanotechnology. The first chapter discusses the synthesis of nanomaterial and mainly the green synthesis of inorganic nanomaterials. Furthermore, a comperative discussion about resistive and capacitive measurement of nano-based biosensor is reviewed and the efficient delivery of nutraceutical with the help of nano-vehicles are explained. Moreover, the book also includes reviews on such topics as nanopharmaceuticals, health benefits and the toxic impact of heavy metal nanomaterials and the impact of several nanomaterials on plant abiotic stress and have focussed on the long term impacts of nanomaterials on agroecosystems. The reader will also find presentations on molecularly imprinted polymeric nanocomposites, critical and comparative comments on Nano-biosensors and Nano-aptasensors and on applications of nanotechnology for the remediation and purification of water with a main focus on drinking water. The last chapter presents a comprehensive review on plasmonic nanoparticle based sensors whereby the authors have hypothesized the future applications in the environment which can be plausible in the near future.
Tectonics of the Indian Subcontinent
This books documents the salient characters of the tectonic evolution of the Indian subcontinent. It showcases the well investigated subcontinent of Gondwana. The book is linked to an updated geological and tectonic map of this region on 1:12,000,000 in scale. The Indian subcontinent displays almost uninterrupted and unique the geological history since about Eo-Archean (~3800 Ma) to recent, with the development of many Proterozoic deformed and metamorphosed fold belts around Archean nuclei, and enormously thick undeformed platform deposits. After their stabilization during late Proterozoic, the subcontinent underwent Paleozoic rifting and deposition of coal-bearing thick sequences, followed by enormously-thick outpouring of Deccan volcanics as a consequence of huge mantle plume. The youngest event in its evolution is the Cenozoic Himalayan Orogenic Mountains, spanning the area between Nanga Parbat and Namcha Barwah; a part of which extends both in Pakistan and Myanmar.
