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Annexins
The Annexins is focused on a specific family of calcium and membrane-binding proteins, annexins, ubiquitously spread within living organisms, including animals, plants and fungi. The volume covers important areas of annexinology. The characterization of structural-functional relationship within the annexin family of proteins, together with emerging transgenic animal models, provides an up-to-date overview of potential physiological roles of annexins. Growing evidence of participation of annexins in human diseases, called annexinopathies, related to disturbances in signal transduction, vesicular traffic, ion homeostasis and energy metabolism within the cell. The book will attract a broad scientific audience, not only scientists interested in annexins, but also others involved in multidisciplinary studies, as well as undergraduate and postgraduate students. It can be used in courses relating to special topics such as calcium homeostasis, calcium-binding proteins, membrane structure and transport properties, various signal transduction pathways, and membrane trafficking.
Irish Children's Literature and Culture
What constitutes a ‘national literature’ is rarely straightforward, and it is especially complex when discussing writing for young people in an Irish context. Until recently, there was only a slight body of work that could be classified as ‘Irish children’s literature’ (whatever the parameters) in comparison with Ireland’s contribution to adult literature in the twentieth century. This volume looks critically at Irish writing for children from the 1980s to the present, examining the work of many writers and illustrators and engaging with all the major forms and genres. Topics include the gothic, the speculative, picturebooks, poetry, post-colonial discourse, identity and ethnicit...
Citizen Science
Citizen science enlists members of the public to make and record useful observations, such as counting birds in their backyards, watching for the first budding leaf in spring, or measuring local snowfall. The large numbers of volunteers who participate in projects such as Project FeederWatch or Project BudBurst collect valuable research data, which, when pooled together, create an enormous body of scientific data on a vast geographic scale. In return, such projects aim to increase participants' connections to science, place, and nature, while supporting science literacy and environmental stewardship. In Citizen Science, experts from a variety of disciplines—including scientists and educati...
High Resolution Chromatography
The molecular biology revolution has required the development of new chromatographic techniques and the optimization of original techniques to give reasonable quantities of protein at high resolutions. The aim of this volume is to provide the necessary information in most experimental situations to enable rapid and effective purification. The first four chapters deal with the instrumental aspects of high resolution chromatography starting with the initial clean up steps prior to separation in chapter 1. Chapter 2 deals with microscale techniques, then chapter 3 describes the detector technologies that can determine information about the separated molecules. The final chapter in this section ...
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Animal Lectins: Form, Function and Clinical Applications
Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular distribution, molecular structure, gene organization, possible functions, clinical applications, lectin-ligand interactions and their intervention for therapeutic purposes are provided. The recently discovered C-type lectins as well as further novel super-families of this group of molecules are described in detail. Furthermore, the clinical significance of animal lectins in inflammatory diseases, defects of immune defense and autoimmunity are described and their application as drugs and therapeutic targets is discussed. With the increasing interest in lectins in biomedical research and their therapeutic applications, this book on animal lectins and associated proteins is a must have for researchers in the area.
Textbook of Palliative Care Communication
The Textbook of Palliative Care Communication is the authoritative text on communication in palliative care, providing a compilation of international and interdisciplinary perspectives. The volume was uniquely developed by an interdisciplinary editorial team to address an array of providers including physicians, nurses, social workers, and chaplains, and unites clinicians with academic researchers interested in the study of communication. By featuring practical conversation and curriculum tools stemming from research, this text integrates scholarship and inquiry into translatable content that others can use to improve their practice, teach skills to others, and engage in patient-centered com...
Jurist Prudent -- The Judicial Opinions of Lawrence L. Koontz, Jr., Volume 3
Upon his retirement from active service as a Justice of the Supreme Court of Virginia in 2011, Justice Koontz had completed more than four decades of service to citizens of the Commonwealth of Virginia. In order to recognize that service and help preserve Justice Koontz's legacy as one of the outstanding jurists in Virginia and the United States, the Salem/Roanoke County Bar Association instituted this project to collect all of Justice Koontz's published opinions, both from his tenure as a Justice of the Supreme Court and as an inaugural member of the Court of Appeals of Virginia. This volume is dedicated to the memory of Judge Bernard G. Barrow, one of the "gang of ten" original members of the Court of Appeals. In January 1995, Judge Barrow announced his intention to retire from the Court in June of that year. Sadly, just over two month before his retirement would be come effective, Judge Barrow suffered a fatal seizure and died on March 21, 1995.
