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Morphine and other opioids are potent analgesic drugs, but their use can lead to complications. Being familiar with the use of this kind of drug can make the difference between obtaining the expected benefit of applied therapy or magnifying the risks to intolerable levels for the patient. Therefore, it is essential for practitioners to achieve adequate training in the management of these drugs based on criteria endorsed by scientific evidence that allows the proper use of these drugs and guarantees the best professional practice every time. Written by expert authors in the field, the purpose of this book is to offer an overview of opioid drugs, from their therapeutic use to the consequences associated.
The use and misuse of drugs is a major social, health, political and economic issue globally. This book presents a series of chapters on the impact of drug use during pregnancy; the impact of parental drug addiction on the child with recommendations for supporting children and teenagers during a parents recovery process; the development of parental skills and renewed parent-child bonding; and how improvements in positive child outcomes can result from an inter-agency working between child protection and addiction treatment providers.
This book addresses opioids and opioid use disorders from epidemiological, clinical, and public health perspectives. It covers detailed information on the nature of opioids, their effects on the human body and brain, prevention, and treatment of opioid addiction. Unlike other texts, the first section of this volume builds a strong historical, neurobiological, and phenomenological foundation for a deep understanding of the topic and the patient. The second section addresses the most challenging issues clinicians face, including pharmacological and psychosocial treatments, harm reduction approaches, alternative approaches to pain management for the non-specialist, and prescribing guidelines. Treating Opioid Addiction is a valuable resource for psychiatrists, psychologists, addiction medicine physicians, primary care physicians, drug addiction counselors, students, trainees, scholars, and public health officials interested in the effects and impact of opioids in the clinical and epidemiological context.
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Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan:...
This book presents an updated discussion of the chemical composition and biological properties of the main bee products. Specific attention is focused on the beneficial biological activities of bee products in human health. Honey, royal jelly, propolis, bee pollen and bee venom are used as nutriment and in traditional medicine. Their composition is rather variable and depends on the floral source and external factors, such as seasonal, environmental conditions and processing. Bee products are rich in several essential nutrients and non essential nutrients, as sugars, minerals, proteins, free amino acids, vitamins, enzymes and polyphenols, that seem to be closely related to their biological functions. The effects of these products in nutrition, aging and age-related diseases, cancer, neurodegenerative diseases and pathogen infections are discussed.
What arouses an animal or human from an inactive, nonresponsive state to a condition of activity and responsiveness? What are the biological mechanisms for this change? In this book Donald W. Pfaff focuses on a reproductive behavior typical of many female animals. Sensory stimuli from the male trigger responses in a well-defined circuit of nerve cells. At the top of the circuit, certain nerve cells receive and retain sex hormones such as estrogens and progesterone. As a result, specific genes in these nerve cells are turned on at specific times, affecting in turn the rest of the neural circuit and causing a state of sexual responsiveness. According to Pfaff, the biological bases for the most primitive human drives are largely explained by mechanisms uncovered in animal brains that have not changed in their fundamental properties over millions of years of evolution. Focusing on a single instinctive behavior, in this case the sex drive, is an important step toward understanding the biological reasons for the change from unmotivated to motivated animal behavior.
Biological invasions by alien (non-native) species are widely recognized as a significant component of human-caused global environmental change and the second most important cause of biodiversity decline. Alien species threaten many European ecosystems and have serious environmental, economic and health impacts. The DAISIE (Delivering Alien Invasive Species Inventories for Europe) project has now brought together all available information on alien species in Europe (terrestrial, aquatic and marine) and from all taxa (fungi, plants, animals). Thus for the first time, an overview and assessment of biological invasions in the Pan-European region is finally possible. The Handbook of Alien Specie...