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Origin and Evolution of Viruses
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. - NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution - UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups - SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
Are We the Next Endangered Species?
Are We the Next Endangered Species? unravels the complex web of historical events, misinformation, and the ominous convergence of bioweapons and eugenics In this thought-provoking new book, Dr. Fleming challenges us to navigate the murky waters of history, exposing parallel programs developed over the last 170 years in the United States. This riveting exploration unearths ancient civilizations that embraced slavery, sterilization, and eugenics, drawing chilling parallels to our present reality. Dr. Fleming confronts the uncomfortable truth: are we repeating the mistakes of the past while expecting different outcomes? Are we destined to replicate the errors that led to the rise of powerful in...
Viral Fitness and Evolution
This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
Viruses as Complex Adaptive Systems
How complex systems theory sheds new light on the adaptive dynamics of viral populations Viruses are everywhere, infecting all sorts of living organisms, from the tiniest bacteria to the largest mammals. Many are harmful parasites, but viruses also play a major role as drivers of our evolution as a species and are essential regulators of the composition and complexity of ecosystems on a global scale. This concise book draws on complex systems theory to provide a fresh look at viral origins, populations, and evolution, and the coevolutionary dynamics of viruses and their hosts. New viruses continue to emerge that threaten people, crops, and farm animals. Viruses constantly evade our immune sy...
Variation and Evolution in Plants and Microorganisms
"The present book is intended as a progress report on [the] synthetic approach to evolution as it applies to the plant kingdom." With this simple statement, G. Ledyard Stebbins formulated the objectives of Variation and Evolution in Plants, published in 1950, setting forth for plants what became known as the "synthetic theory of evolution" or "the modern synthesis." The pervading conceit of the book was the molding of Darwin's evolution by natural selection within the framework of rapidly advancing genetic knowledge. At the time, Variation and Evolution in Plants significantly extended the scope of the science of plants. Plants, with their unique genetic, physiological, and evolutionary features, had all but been left completely out of the synthesis until that point. Fifty years later, the National Academy of Sciences convened a colloquium to update the advances made by Stebbins. This collection of 17 papers marks the 50th anniversary of the publication of Stebbins' classic. Organized into five sections, the book covers: early evolution and the origin of cells, virus and bacterial models, protoctist models, population variation, and trends and patterns in plant evolution.
Advances in Virus Research
Advances in Virus Research, Volume 106, the latest in the series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.
Critical Population and Error Threshold on the Sharp Peak Landscape for a Moran Model
The goal of this work is to propose a finite population counterpart to Eigen's model, which incorporates stochastic effects. The author considers a Moran model describing the evolution of a population of size of chromosomes of length over an alphabet of cardinality . The mutation probability per locus is . He deals only with the sharp peak landscape: the replication rate is for the master sequence and for the other sequences. He studies the equilibrium distribution of the process in the regime where
The Three Pillars of Evolution Demolished
The three pillars of evolution, defined as progression from simple molecules to humans, are the origin of life and genetic damage called mutations selected by natural selection. Dr. Bergman documents that the peer reviewed scientific literature has demolished these central pillars of evolution, specifically the origin of life from non-life and the source of genetic variety called mutations honed by natural selection. As genetic research of life has been shown to be increasingly more complex, life from nonlife by natural means is now no longer feasible. Furthermore, most all mutations are partly or wholly deleterious and natural selection serves primarily to reduce the deterioration of life, not evolve life to greater levels of complexity as evolution postulates. In short. the naturalistic evolutionary theory first expounded by Charles Darwin has been falsified by scientific research.
The Secret in Medieval Literature
The Secret in Medieval Literature explores the many secret agents, actions, creatures, and other beings influencing human existence. Medieval poets had a clear sense of the alternative dimension (the secret) and allowed it to enter quite frequently into their texts.
Plasticity in the Life Sciences
Analyzes the reasons why biologists have referred to and continue to refer to plasticity. Plasticity has become an important topic in biology, with some even wondering if it has now acquired the theoretical importance in biology that the concept of the gene enjoyed at the beginning of the last century. In this historical and epistemological study, philosopher Antonine Nicoglou shows how the recurrence of the general idea of plasticity—throughout the history of the life sciences—indicates its essential role in the way we think about life processes. Although plasticity has become a key element in new evolutionary thinking, she argues, its role in contemporary biology is also not insignific...
