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Science
A weekly record of scientific progress.
Pediatric Pharmacotherapy
This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction
Pulmonary hypertension (PH) is a disorder of the pulmonary vasculature defined by increased mean pulmonary arterial pressure (mPAP) leading to right ventricle (RV) hypertrophy and dysfunction, right-sided heart failure and ultimately death. PH is a common complication of chronic lung diseases (CLD) including idiopathic pulmonary fibrosis (IPF) or chronic obstructive pulmonary disease (COPD) where it is classified as Group 3 PH by the WHO. It can also be associated with cardiovascular conditions such as left-heart disease (classified as Group 2 PH) or appear on its own as pulmonary arterial hypertension (PAH) and classified as Group1 PH. In all of these cases the diagnosis of pulmonary hypertension is strongly associated with increased morbidity and mortality. The focus of this Research Topic is to enhance our understanding of the mechanisms that contribute to the pathophysiology of pulmonary hypertension and right ventricle hypertrophy.
Latin and Greek Monasticism in the Crusader States
The first comprehensive survey of monasteries and monasticism in the Near East during the 'Crusader' period.
Federal Register
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Habent sua fata libelli
Habent sua fata libelli honors the work of Craig Kallendorf, offering studies in several fields in which he chiefly distinguished himself: the history of the book and reading, the classical tradition and reception studies, Renaissance humanism, and Virgilian scholarship with a special focus on the creative transformation of the Aeneid through the centuries. The volume is rounded out by an appreciation of Craig Kallendorf, including a review of his scholarship and its significance. In addition to the topics mentioned above, the volume’s twenty-five contributions are of relevance to those working in the fields of classical philology, Neo-Latin, political philosophy, poetry and poetics, print...
State Magazine
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State
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