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HER2-Positive Breast Cancer
Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.
Antibody-Drug Conjugates
Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development
Encyclopedia of Judaism
An illustrated A to Z reference containing over 800 entries providing information on the theology, people, historical events, institutions and movements related to the religion of Judaism.
Antibody-Drug Conjugates
Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development
Sara
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Drugs and the FDA
How the FDA was shaped by public health crises and patient advocacy, told against a background of the contentious hearings on the breast cancer drug Avastin. Food and Drug Administration approval for COVID-19 vaccines and the controversial Alzheimer’s drug Aduhelm made headlines, but few of us know much about how the agency does its work. Why is the FDA the ultimate US authority on a drug’s safety and efficacy? In Drugs and the FDA, Mikkael Sekeres—a leading oncologist and former chair of the FDA’s cancer drug advisory committee—tells the story of how the FDA became the most trusted regulatory agency in the world. It took a series of tragedies and health crises, as well as patient ...
PI3K-mTOR in Cancer and Cancer Therapy
In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority o...
Religious Leadership
This title tackles issues relevant to leadership in the realm of religion. It explores such themes as the contexts in which religious leaders move, leadership in communities of faith, leadership as taught in theological education and training, religious leadership impacting social change and social justice, and more. Topics are examined from multiple perspectives, traditions, and faiths.
CMDT 2017 eBook ValPak: CMDT 2017 and Study Guide, Second Edition
SAVE WHEN YOU BUY THE CMDT VALUE PACK – AND TAP INTO THE EXPERTISE OF THE #1 ANNUAL BOOK IN INTERNAL MEDICINE! This dollar-saving package includes: CURRENT Medical Diagnosis & Treatment 2017 CMDT is the most successful annual book covering the field of internal medicine and has been acclaimed for its comprehensive coverage of current inpatient and outpatient care, diagnostic tools relevant to day-to-day practice, and full review of all primary care topics. In addition to its use as a reference text, CMDT is outstanding as a core clinical textbook for medical students and nurse practitioner and physician assistant students to study for a variety of exams in a variety of medical and health-r...
From Bards to Biblical Exegetes
A cursory glance through the Psalter reveals numerous allusions to events in Israel's literary history. While a range of literary and oral sources were obviously available to psalmists, the relationships between these sources and the psalmists' final work are more obscure. Concerning these relationships, numerous questions remain unanswered: - How strictly did the psalmists replicate their sources? - What kinds of alterations did they make (additions, omissions, etc.)? - Did they alter the meaning of their sources in their own compositions? Departing from the more classical approaches to researching the psalms--engaging in the determination of Sitz im Leben and Gattungen--this intertextual s...
