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Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today's available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists. - Covers the diagnosis, treatments and targeted therapies, and management of breast cancers that are HER2-positive. - Contains sections on background and testing, advanced disease, therapeutics, and toxicity considerations. - Includes a timely section on innovative future therapies.
Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development
An illustrated A to Z reference containing over 800 entries providing information on the theology, people, historical events, institutions and movements related to the religion of Judaism.
Out of Athens sets ancient Greek culture next to the global ancient world of Vedic India, the Han dynasty in China, and the empires that survived Alexander the Great.--Publisher description.
Some of America’s best reporters and thinkers offer an urgent look at a country in chaos in this collection of timely, often prophetic articles from The Atlantic. The past four years in the United States have been among the most turbulent in our history—and would have been so even without a global pandemic and waves of protest nationwide against police violence. Drawn from the recent work of The Atlantic staff writers and contributors, The American Crisis explores the factors that led us to the present moment: racial division, economic inequality, political dysfunction, the hollowing out of government, the devaluation of truth, and the unique threat posed by Donald Trump. Today’s emerg...
Professor Menahem Haran is honored in this volume by a chorus of colleagues, disciples, and friends from Israel, Europe, North America, and the Far East. The diversity of Haran's expertise is reflected in the table of contents of this collection, organized around the topics: "Priests and Their Sphere," "The Torah," "The Prophets," "The Writings," and "Language and Writing.
A cursory glance through the Psalter reveals numerous allusions to events in Israel's literary history. While a range of literary and oral sources were obviously available to psalmists, the relationships between these sources and the psalmists' final work are more obscure. Concerning these relationships, numerous questions remain unanswered: - How strictly did the psalmists replicate their sources? - What kinds of alterations did they make (additions, omissions, etc.)? - Did they alter the meaning of their sources in their own compositions? Departing from the more classical approaches to researching the psalms--engaging in the determination of Sitz im Leben and Gattungen--this intertextual s...
This title tackles issues relevant to leadership in the realm of religion. It explores such themes as the contexts in which religious leaders move, leadership in communities of faith, leadership as taught in theological education and training, religious leadership impacting social change and social justice, and more. Topics are examined from multiple perspectives, traditions, and faiths.