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One of the major considerations of any environmental resource project must be the effect on human well-being; originally published in 1979, this study aims to deal specifically with the transmission of Schistosomiasis as a human environmental impact. Due to its relationship with water, Schistosomiasis transmission areas can be spread or aggravated by new water resource projects particularly in developing countries, which could potentially lead to an epidemic situation. Rosenfield aims to demonstrate how prevention ideas can be conceived early on in the design process by exploring methodologies for predicting the prevalence of Schistosomiasis in certain areas and management strategies for controlling transmission. This title will be of interest to students of Environmental Studies and professionals.
An estimated 200 million people in the world suffer from schistosomiasis (bilharzia), and according to the World Health Organization it ranks second behind malaria in terms of socioeconomic and public health importance in tropical and subtropical areas. The disease was present in Egypt in the Old Kingdom (c. 2600 BCE), and in 1998 it was estimated that almost six million Egyptians -- one fifth of the rural population -- were infected. Thus it remains one of the most serious public health problems in rural Egypt. This study is the first to paint a broad picture of schistosomiasis in rural Egypt. The authors' research in three Nile Delta villages between 1991 and 1997 provides an in-depth comm...
Reports on schistosomiasis epidemiology and clinical features in Africa and Brazil, and development of novel drugs that affect the worm tegument, and vaccine based on excretory-secretory products and Type 2 cytokines.
A comprehensive guide to the technical and practical factors that need to be considered when designing and implementing programmes for the control of schistosomiasis. Noting the success of strategies focused on morbidity control, the report shows how the spectrum of programme goals can now be broadened to include reductions in the prevalence and intensity of established infections and decreases in the intensity of transmission. Throughout, emphasis is placed on knowledge and experiences that can help programme managers establish feasible goals and then select control options in line with the form of infection, its public health importance, the degree and type of morbidity, available resource...
This volume brings together updated fundamental knowledge of the schistosomes, their biology and epidemiology, the mechanism of disease and a full description of the pathological sequelae and clinical syndromes in humans. It concludes with chapters on diagnosis and treatment prospects of vaccine development and the most significant controversies regarding immunology and epidemiology. Contents: Schistosomiasis: Setting the Stage (A AF Mahmoud); The Schistosomes and Their Intermediate Hosts (R F Sturrock); The Structure and Expression of the Schistosome Genome (G R Franco & A JG Simpson); Epidemiology of Schistosomiasis: Determinants of Transmission of Infection (C H King); Resistance to Infec...
Schistosomiasis is Africa's second most common parasitic disease. Less than 20 years ago, over 200 million were infected. In many high-risk areas the Schistosomiasis Control Initiative (SCI) has been helping to tackle the disease by offering treatments to millions of children. This book tells the story of a man, Alan Fenwick, who founded the SCI to control the worms and snails and so improve the lives of many burdened with the disease as well as reducing the numbers infected. Over this period SCI and the Ministries of Health and Education in 16 countries delivered over 220 million treatments. Treatment coverage of up to 75% has been achieved. Widely recognised as a cost-effective and successful intervention, SCI's knock-on effects include improving overall physical health, school attendance and future prospects for millions of people.
This book provides insights into the research and programs currently related to schistosomiasis, and uses these insights to project into future years of work on schistosomiasis, from research to public health interventions. A secondary goal is to initiate conversations among those working on schistosomiasis about the future of their field, and by doing so lead to constructive efforts to identify and address the most critical questions and challenges related to schistosomiasis. The first 4 chapters address schistosome phylogenetics, gene expression, and the overall genome. The next 3 chapters explore the host-schistosome interaction at the larval to adult worm interface. The following 3 chapters explore the development of the host immune response to eggs, granuloma formation and factors affecting the development and regulation of immunopathology. The next 4 chapters address public health concerns, and concludes with a chapter addressing the schisms that sometimes exist between basic research to implementation of control schemes.
According to the author, the book addresses to all the scientists and not only to immunologists or biologists of European countries who are engaged in developing a vaccine, or a diagnostic kit or a new drug against the infection or on schistosome evolution. Even these scientists have to visit endemic countries for field trials or ask their counterparts to collect field data (which this book addresses ). Thus this book is not on molecular fundamentals but on the infection itself; how schistosome species are responding to the drug ; sensitivity and specificity of immunodiagnostic kits, antigen molecules; snail compatibility, production losses; schistosome evolution; schistosome outbreaks; complexities where more than two schistosome species are existing; problem of human schistosomiasis in South Asia etc In fact , all the topics of great interest to international scientists and scientists of endemic countries.
3597 references obtained from Tropical diseases bulletin, Helminthological abstracts, and MEDLARS data base. Worldwide coverage. Mostly journal articles. Alphabetical arrangement by primary authors. Each entry includes bibliographical information, abstract, and source of abstract. Author, keyword indexes.