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Dengue
This unique volume presents an up-to-date review of one of the world's major health problems -- diseases caused by the four dengue viruses. It begins with an insightful story of the origin of dengue disease outbreaks, including the emergence of severe and fatal dengue hemorrhagic fever. The nature, structure and biology of the four dengue viruses are described, and a major portion of the book is focused on the epidemiology of dengue as a mosquito-borne disease. This is complemented by critiques of existing mosquito control programs by three groups of outstanding authorities. The strongest element of the volume is its comprehensive description of the current understanding of dengue disease pathogenesis, followed by an analysis of the pros and cons of five of the most controversial areas in the field: the WHO DEF case definition, secondary dengue infections, virulent viruses, the role of abnormal T cells and autoimmunity.
The Politics of International Health
Tracing the history of the Children's Vaccine Initiative (CVI), this book examines its successes and failures in promoting the development of both new and improved vaccines for the Third World. The CVI has achieved many successes, including making vaccination a top international public sector priority. Most of its failures have stemmed from the often bitter competition between the fledgling Initiative and the notoriously turf-conscious and inefficient World Health Organization (WHO), over their respective roles in championing vaccines. Vaccines are the most inexpensive means of improving the health and lowering the mortality of people in the Third World, where infectious diseases kill millions of children every year. As a result of the biotechnology revolution, it is possible that a whole array of new vaccines can be created for diseases which are not yet preventable. What has stood in the way of this major medical breakthrough has been that vaccine "product development" has been in the hands of commercial companies, whose activities are dominated by the need for maximizing profit, which the Third World poor cannot generate.
Vaccines: A Biography
Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natu...
Arboviruses
Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research li...
Water and Sanitation-Related Diseases and the Changing Environment
The revised and updated second edition of Water and Sanitation Related Diseases and the Changing Environment offers an interdisciplinary guide to the conditions responsible for water and sanitation related diseases. The authors discuss the pathogens, vectors, and their biology, morbidity and mortality that result from a lack of safe water and sanitation. The text also explores the distribution of these diseases and the conditions that must be met to reduce or eradicate them. The text includes contributions from authorities from the fields of climate change, epidemiology, environmental health, environmental engineering, global health, medicine, medical anthropology, nutrition, population, and...
Dengue and Dengue Hemorrhagic Fever, 2nd Edition
Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. Recent exciting research on dengue has resulted in major advances in our understanding of all aspects of the biology of these viruses, and this updated second edition brings together leading research and clinical scientists to review dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management.
Nelson Textbook of Pediatrics, 2-Volume - E-Book
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Pediatrics**Covering every aspect of general pediatric practice, as well as details for many pediatric subspecialists, Nelson Textbook of Pediatrics, 22nd Edition, brings you fully up to date with everything from rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today. Edited and written by experts and prominent members of the pediatric medical community, this comprehensive two-volume reference covers both the science and art of pediatric practice. It remains the reference of choice among pediatricians, pedi...
Dengue and Dengue Hemorrhagic Fever in the Americas
Dengue and its potentially fatal forms, dengue henorrhagic fever and dengue shock syndrome, once more threaten much of the Americas. In the 1980s the vector control programmes fell victim to the cutbacks in public health expenditure and their responses to dengue outbreaks tended to be a little too late. These guidelines have risen to the challenge by incorporating all aspects of the prevention and control of the disease and its vectors. In addition, because dengue is primarily a problem of domestic sanitation and households can combat the problem inexpensively. The guidelines enmphasize ways to transfer responsibility for dengue control and prevention to the community."
Antibody Fc
Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology. Antibodies represent the correlate of protection for numerous vaccines and are the most rapidly growing class of drugs, with applications ranging from cance...
Dengue
This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.
