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While cities often act as the engines of economic growth for developing countries, they are also frequently the site of growing violence, poverty, and inequality. Yet, social theory, largely developed and tested in the Global North, is often inadequate in tackling the realities of life in the dangerous parts of cities in the Global South. Drawing on the findings of an ambitious five-year, 15-project research programme, Social Theories of Urban Violence in the Global South offers a uniquely Southern perspective on the violence–poverty–inequalities dynamics in cities of the Global South. Through their research, urban violence experts based in low- and middle-income countries demonstrate ho...
The human brain and its one hundred billion neurons compose the most complex organ in the body and harness more than 20% of all the energy we produce. Why do we have such large and energy-demanding brains, and how have we been able to afford such an expensive organ for thousands of years? Guts and Brains discusses the key variables at stake in such a question, including the relationship between brain size and diet, diet and social organization, and large brains and the human sexual division of labor. Showcasing how small changes in the diet of early hominins came to have large implications for the behavior of modern humans, this interdisciplinary volume provides an entry for the reader into understanding the development of both early primates and our own species.
This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. It is understood and presented as a phenomenon of crucial relevance for a large variety of processes and materials. In this book, all aspects of the theoretical fundamentals, experimental techniques, highlights of current developments and results for solids, liquids and interfaces are presented.
This book provides an overview of the world market of therapeutic enzymes and enzyme inhibitors, rare diseases, orphan drugs, the costs of drug development and therapies, and enzymes in downstream processing of pharmaceuticals. It discusses carbonic anhydrase inhibitors and their multiple drug interactions, carboxylesterase inhibitors for pharmaceutical applications, employment of inhibitors for the treatment of neurodegenerative diseases, use of engineered proteins, bioactive peptides, and fibrinolytic enzymes for thrombolytic therapy, and enzymes important for the design and development of new drugs/drug metabolites such as aldehyde oxidases and cytochrome P450 enzymes and the role the lat...
Presents a multi-disciplinary perspective on the physics of life and the particular role played by lipids and the lipid-bilayer component of cell membranes. Emphasizes the physical properties of lipid membranes seen as soft and molecularly structured interfaces. By combining and synthesizing insights obtained from a variety of recent studies, an attempt is made to clarify what membrane structure is and how it can be quantitatively described. Shows how biological function mediated by membranes is controlled by lipid membrane structure and organization on length scales ranging from the size of the individual molecule, across molecular assemblies of proteins and lipid domains in the range of nanometers, to the size of whole cells. Applications of lipids in nano-technology and biomedicine are also described.
This collection of papers arises from a meeting of distinguished scholars at Tautavel in 1993, sponsored by the European Science Fund. The aim of the meeting was to discuss and review the evidence for the earliest occupation of different European regions, from Scandinavia to the Mediterranean and from the United Kingdom to the Russian Plains and including neighbouring areas such as the Caucasus and Northern Africa. Discussion focused on four themes: chronology, environment, industries and subsistence. The central dispute between proponents of the Long chronology (placing the first hominids in Europe almost 2m years ago) and the supporters of a Short chronology (no hominids until 500,000 years ago) is covered in detail. The disputed 1.5m years are crucial to our understanding of how our earliest ancestors adapted to the European environment and this book will be crucial in furthering the debate.
International Lithosphere Program; Publ. No. 0104
Sophie is entering her last year of college, and is doing all the normal things. Taking classes. Dating. Thinking about a Masters Degree. Helping in her community. Being a Witch. You know, the usual.But when an ordinary student paper gets her embroiled in a life or death game with one of the largest Tech Conglomerates in the world, Sophie must choose. Will she follow in the occult traditions passed down to witches over the centuries, and back out of the fray? Or will she fight for what's right, even going to lengths she knows are wrong?And, when the dust settles, just which sort of witch will she end up being?Trigger Warnings: Discussion of rape, suicide. Depiction of self-harm.
"This book tells the story of the poor, often indigenous workers living in the borderlands who are recruited to work in the lowest echelons of the drug trade, as burreros (mules) and narcotraficantes (traffickers). Shayleh Muehlmann spent over a year researching in a small community in the borderlands. This book brings her stories to a wider public, narrating the experiences of a group of indigenous fishermen in northern Mexico who have become involved in the drug trade, and exploring how the narco-economy has provided a reprieve for men and women attempting to survive while their primary form of livelihood, fishing, has been criminalized by the state because of its alleged negative environm...