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Bacterial pathogens in the non-clinical environment
  • Language: en
  • Pages: 102

Bacterial pathogens in the non-clinical environment

The transmission route used by many bacterial pathogens of clinical importance includes a step outside the host; thereafter refer to as the non-clinical environment (NCE). Obvious examples include foodborne and waterborne pathogens and also pathogens that are transmitted by hands or aerosols. In the NCE, pathogens have to cope with the presence of toxic compounds, sub-optimal temperature, starvation, presence of competitors and predators. Adaptation of bacterial pathogens to such stresses affects their interaction with the host. This Research Topic presents important concept to understand the life of bacterial pathogens in the NCE and provides the reader with an overview of the strategies used by bacterial pathogens to survive and replicate outside the host.

Biology and Pathogenesis of Legionella
  • Language: en
  • Pages: 181

Biology and Pathogenesis of Legionella

Legionella pneumophila was first isolated as the causative agent of a deadly infectious pneumonia at a convention of the American Legion forty years ago. Since then, Legionnaires’ disease continues to be a significant public health concern. Today, our understanding of the Legionella genus, comprising environmental bacteria and opportunistic human pathogens, has dramatically increased. The study of how pathogenic Legionella interact with host cells, both protozoan and mammalian, has not only taught us about host-pathogen interactions but has revealed novel and unexpected insights into human cell biology and immunology. The capacity of pathogenic Legionella to commandeer cellular processes s...

Legionella: from protozoa to humans
  • Language: en
  • Pages: 174

Legionella: from protozoa to humans

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Microbial Safety in Water Resources
  • Language: en
  • Pages: 124

Microbial Safety in Water Resources

As more countries become water-scarce, alternative water sources like treated wastewaters will be used to meet the demands of the domestic, agriculture and industrial sectors. However, the use of treated wastewater is only justified when it is without any detrimental impacts on public health, food safety and water quality. To minimize impacts, well-operated treatment plants are important barriers that reduce the amount of contaminants disseminated from wastewaters into the environment during reuse events. Continuous, accurate and comprehensive monitoring on our water further safeguards the public against potential risks. This eBook looks into topics that close the knowledge gaps in these mentioned areas.

Molecular Mechanisms in Legionella Pathogenesis
  • Language: en
  • Pages: 297

Molecular Mechanisms in Legionella Pathogenesis

Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.

The Staphylococci and staphylococcal pathogenesis
  • Language: en
  • Pages: 214

The Staphylococci and staphylococcal pathogenesis

Members of the genus Staphylococcus play important roles in disease causation in humans and animals. Over the past decade, the completed sequencing of many staphylococcal genomes has contributed to a surge in the number of publications, which have promoted a tremendous advance in our knowledge of these important pathogens. Significant developments include the emergence of new and highly virulent strains of S. aureus, advances in tracking the evolution of human and animal adapted strains, a heightened appreciation of the role of mobile genetic elements in antibiotic resistance and pathogenesis, and important insights into staphylococcal physiology, immune evasion strategies, and cell surface proteins, as well as significant advances in vaccine development and therapeutics. This Research Topic will focus attention on the latest developments in these areas as they pertain to S. aureus and members of the coagulase-negative Staphylococci, and will also strive to identify areas of future development.

Can J Microbiol
  • Language: en
  • Pages: 366

Can J Microbiol

  • Type: Book
  • -
  • Published: 2014
  • -
  • Publisher: Unknown

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Proceedings of the National Academy of Sciences of the United States of America
  • Language: en
  • Pages: 1380

Proceedings of the National Academy of Sciences of the United States of America

  • Type: Book
  • -
  • Published: 2006
  • -
  • Publisher: Unknown

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Management of Legionella in Water Systems
  • Language: en
  • Pages: 291

Management of Legionella in Water Systems

Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.