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Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.
In 6,000 food products, aspartame is found everywhere in so-called diet nutrition. However, several scientific studies show that this sweetener is harmful for children, pregnant women and epileptics. Used to replace sugar and reduce the caloric intake of food, aspartame actually works in the opposite direction, it develops obesity and diabetes. In this first in-depth investigation of the diet industry, Henriette Chardak exposes a health scandal. She shows why the use of aspartame continues despite the risks it generates. How people were pushed into consuming these chemical substances—whose harmlessness had been questioned for many years. Between Chicago and Tokyo, top-secret files and comp...
First multi-year cumulation covers six years: 1965-70.
This new edition provides biographical information on 2,000 prominent and distinguished persons in Lebanon, including foreign residents, who by virtue of their achievements in their respective fields or by the influential positions they hold, have gained recognition in public life or in private sections.
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This volume contains an edited selection of the materials, lectures and debates presented at the World Conference on Science, which took place in Budapest in 1999. Topics ranging from the value of fundamental research to the public perception of science and ethical issues are presented.
First multi-year cumulation covers six years: 1965-70.