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Evolution and Eschatology
The genome revolution of the last twenty years has changed biology forever. It has provided stunning insights into the evolution of species (such as ours) and the development of new functional capabilities (such as placenta, brain, and immune networks). We are learning how genes make a human animal―but that loving relationships with others are required to make a human person. Random mutations, filtered by directing order, underlie evolutionary development, but also cause diseases such as cancer. We are wont to question God when faced with devastating natural and moral evils. But deeply embedded in the biblical story we encounter a Creator who has always purposed to deal with the evils of a freely operating world by extirpating them through Jesus of Nazareth, who is God incarnate.
Trends in Neuroimmunology: cross-talk between brain-resident and peripheral immune cells in both health and disease
The functional anatomy of organisms is maintained by the coordination of different systems, that often rely on particular interactions between specialized cells and between macromolecules. The immune system works with the circulatory and the lymphatic systems to protect most of the organs. However, some organs are considered immune privileged due to the presence of highly selective and regulated barriers, such as the blood-brain barrier (BBB) within the brain. The BBB controls periphery-brain molecule exchange and prevents immune effector cells from entering the homeostatic brain. BBB-associated elements, such as endothelial cells, pericytes, astrocytes, and microglia, potentially can functi...
Molecular Medicine
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