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ACE Inhibitors
Angiotensin converting enzyme inhibitors (ACEI) represent the first class of antihypertensive agents that was designed and developed on the basis of a well-defined physiopathological axis of arterial hypertension, a vascular dis order that is now becoming one of the major causes of morbidity/mortality, not only in developed societies but also in the highly populated developing coun tries [1]. CAPTOPRIL, the prototype of the "PRIL" family, which now comprises more than 40 molecule-species, was quite hazardous and the clinical develop ment almost failed when serious side-effects were reported in an alarmist fash ion in reputable scientific journals, such as the New England Journal of Medicine ...
The Rotarian
Established in 1911, The Rotarian is the official magazine of Rotary International and is circulated worldwide. Each issue contains feature articles, columns, and departments about, or of interest to, Rotarians. Seventeen Nobel Prize winners and 19 Pulitzer Prize winners – from Mahatma Ghandi to Kurt Vonnegut Jr. – have written for the magazine.
The Subtle Beast
The Subtle Beast: Snakes, from Myth to Medicine introduces you to the complex and absorbing world of these mysterious creatures. Each of the fourteen chapters in this volume can be read independently, but read together they trace a fascinating journey from the macroscopic features of snakes to the molecular description of their venom components.
Candid Science II
This invaluable book contains 36 interviews, including 26 with Nobel laureates. It presents a cross-section of biomedical science, a field that has been dominant in science for the past half century. The in-depth conversations cover important research areas and discoveries, as well as the roads to these discoveries, including aspects of the scientists' work that never saw publication. They also bring out the humanness of the famous scientists — the reader learns about their backgrounds, aspirations, failings, and triumphs. The book is illustrated with snapshots of the conversations and photos provided by the interviewees. It is a follow-up to the critically acclaimed Candid Science: Conver...
Biomass Wastes for Energy Production
Environmental problems are forcing a rethinking of the world’s energy supply system. In parallel, there is an increasing amount of global solid waste production. A fundamental shift toward greater reliance on biomass wastes in the world’s energy system is plausible because of ongoing major technological advances that hold the promise of making the conversion of biomass into high-quality energy carriers, like electricity and gaseous or liquid fuels, economically competitive with fossil fuels. Therefore, waste-to-energy systems have become a paramount topic for both industry and researchers due to interest in energy production from waste and improved chemical and thermal efficiencies with more cost-effective designs. This biomass shift is also important for industries to become more efficient by using their own wastes to produce their own energy in the light of the circular economy concept. This book on “Biomass Wastes for Energy Production” brings novel advances on waste-to-energy technologies, life cycle assessment, and computational models, and contributes to promoting rethinking of the world’s energy supply systems.
Hallelujah Moments
"This work provides eleven stories of drug discovery and features the scientists who made them. The outcome of the discovery work has provided novel therapies in cancer, cardiovascular medicine, antibacterial and antiviral infectious diseases, parasitic diseases, metabolic diseases, and weight control. Each story begins with the basic biomedical science that revealed the pathway to effective drug therapy and continues with the step-by-step process that leads from insight to a product in clinical practice meeting a defined medical need. The tales feature creative problem solving by clever and dedicated scientists as they overcame roadblocks to success., hallelujah moments. Each drug discovery story reflects the interface between basic science, medicine, and drug discovery. Embedded in these tales are the societal and medical environments in which drug discovery takes place, the discovery of agents to treat HIV/AIDS, for example. Finally, a series of appendices provides basic chemical background for non-scientists"--
