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ACE Inhibitors
Angiotensin converting enzyme inhibitors (ACEI) represent the first class of antihypertensive agents that was designed and developed on the basis of a well-defined physiopathological axis of arterial hypertension, a vascular dis order that is now becoming one of the major causes of morbidity/mortality, not only in developed societies but also in the highly populated developing coun tries [1]. CAPTOPRIL, the prototype of the "PRIL" family, which now comprises more than 40 molecule-species, was quite hazardous and the clinical develop ment almost failed when serious side-effects were reported in an alarmist fash ion in reputable scientific journals, such as the New England Journal of Medicine ...
The Rotarian
Established in 1911, The Rotarian is the official magazine of Rotary International and is circulated worldwide. Each issue contains feature articles, columns, and departments about, or of interest to, Rotarians. Seventeen Nobel Prize winners and 19 Pulitzer Prize winners – from Mahatma Ghandi to Kurt Vonnegut Jr. – have written for the magazine.
The Subtle Beast
The Subtle Beast: Snakes, from Myth to Medicine introduces you to the complex and absorbing world of these mysterious creatures. Each of the fourteen chapters in this volume can be read independently, but read together they trace a fascinating journey from the macroscopic features of snakes to the molecular description of their venom components.
Kinins
This handbook of kinin biology and biochemistry covers the current knowledge of kinins, a family of peptides involved in numerous physiological and pathophysiological processes. Recent publications have shown that the kinin system is highly relevant in a variety of disease states such as diabetes, multiple sclerosis and traumatic injuries. Furthermore, the first drug targeting system has just been approved for clinical use. The goal of this book is to provide advanced students and researchers a basic understanding of the kinin system and its role within the various organ systems. The authors of this book are experts in their fields, including a Nobel Laureate.
Drugs
In this second edition, Les Iversen presents an introductory account of what drugs are, how they work, and the advances made over the past 100 years in the field of pharmacology. Looking at pharmaceutical drugs and both legal and illegal recreational drugs, Iversen reflects on how twentieth-century drugs have changed our lives.
Catharsis
The ancient Greeks used the term catharsis for the cleansing of both the body by medicine and the soul by art. In this inspiring book, internationally renowned cardiologist Andrzej Szczeklik draws deeply on our humanistic heritage to describe the artistry and the mystery of being a doctor. Moving between examples ancient and contemporary, mythological and scientific, Catharsis explores how medicine and art share common roots and pose common challenges. The process of diagnosis, for instance, belongs to a world of magic and metaphor; the physician must embrace it like a poem or painting, with particular alertness and keen receptivity. Speculation on ways to slow aging through genetics, meanwh...
Edge of the Universe
An accessible look at the mysteries that lurk at the edge of the known universe and beyond The observable universe, the part we can see with telescopes, is incredibly vast. Yet recent theories suggest that there is far more to the universe than what our instruments record—in fact, it could be infinite. Colossal flows of galaxies, large empty regions called voids, and other unexplained phenomena offer clues that our own "bubble universe" could be part of a greater realm called the multiverse. How big is the observable universe? What it is made of? What lies beyond it? Was there a time before the Big Bang? Could space have unseen dimensions? In this book, physicist and science writer Paul Ha...
Introduction to Translational Cardiovascular Research
The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and t...
Drugs and Democracy in Rio de Janeiro
Taking an ethnographic approach to understanding urban violence, Enrique Desmond Arias examines the ongoing problems of crime and police corruption that have led to widespread misery and human rights violations in many of Latin America's new democracies. Employing participant observation and interview research in three favelas (shantytowns) in Rio de Janeiro over a nine-year period, Arias closely considers the social interactions and criminal networks that are at the heart of the challenges to democratic governance in urban Brazil. Much of the violence is the result of highly organized, politically connected drug dealers feeding off of the global cocaine market. Rising crime prompts repressi...
