You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Precision medicine seeks to use data to construct principled, i.e., evidence-based, treatment strategies that dictate where, when, and to whom treatment should be applied. This book provides an accessible yet comprehensive introduction to statistical methodology for dynamic treatment regimes.
None
This book provides a general framework for learning sparse graphical models with conditional independence tests. It includes complete treatments for Gaussian, Poisson, multinomial, and mixed data; unified treatments for covariate adjustments, data integration, and network comparison; unified treatments for missing data and heterogeneous data; efficient methods for joint estimation of multiple graphical models; effective methods of high-dimensional variable selection; and effective methods of high-dimensional inference. The methods possess an embarrassingly parallel structure in performing conditional independence tests, and the computation can be significantly accelerated by running in paral...
Bayesian Nonparametrics for Causal Inference and Missing Data provides an overview of flexible Bayesian nonparametric (BNP) methods for modeling joint or conditional distributions and functional relationships, and their interplay with causal inference and missing data. This book emphasizes the importance of making untestable assumptions to identify estimands of interest, such as missing at random assumption for missing data and unconfoundedness for causal inference in observational studies. Unlike parametric methods, the BNP approach can account for possible violations of assumptions and minimize concerns about model misspecification. The overall strategy is to first specify BNP models for o...
Energy distance is a statistical distance between the distributions of random vectors, which characterizes equality of distributions. The name energy derives from Newton's gravitational potential energy, and there is an elegant relation to the notion of potential energy between statistical observations. Energy statistics are functions of distances between statistical observations in metric spaces. The authors hope this book will spark the interest of most statisticians who so far have not explored E-statistics and would like to apply these new methods using R. The Energy of Data and Distance Correlation is intended for teachers and students looking for dedicated material on energy statistics...
Emerging technologies generate data sets of increased size and complexity that require new or updated statistical inferential methods and scalable, reproducible software. These data sets often involve measurements of a continuous underlying process, and benefit from a functional data perspective. Functional Data Analysis with R presents many ideas for handling functional data including dimension reduction techniques, smoothing, functional regression, structured decompositions of curves, and clustering. The idea is for the reader to be able to immediately reproduce the results in the book, implement these methods, and potentially design new methods and software that may be inspired by these a...
Mixture models are a powerful tool for analyzing complex and heterogeneous datasets across many scientific fields, from finance to genomics. Mixture Models: Parametric, Semiparametric, and New Directions provides an up-to-date introduction to these models, their recent developments, and their implementation using R. It fills a gap in the literature by covering not only the basics of finite mixture models, but also recent developments such as semiparametric extensions, robust modeling, label switching, and high-dimensional modeling. Features Comprehensive overview of the methods and applications of mixture models Key topics include hypothesis testing, model selection, estimation methods, and ...
Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment op...
Reunited ex-friends become lovers in this novella about a woman’s holiday homecoming from a New York Times–bestselling author. After a messy breakup, Leigh Holloway is ready to start her life over. Until her parents put the family home on the market and call her back for one final, memory-making Christmas. The last thing she wants to do is deprive her mom of the perfect holiday, so she’ll lie her way through the visit and worry about her future in the New Year. Too bad the only bar in town is owned by a guy she seriously wronged in high school. Leigh’s best friend broke Croy Dawson’s heart, and Croy knows it was Leigh’s fault. They’ve never liked each other, but Croy isn’t cr...