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Immunotherapy and Small Molecule Inhibitors as Combinational Cancer Therapeutics
  • Language: en
  • Pages: 234

Immunotherapy and Small Molecule Inhibitors as Combinational Cancer Therapeutics

Cancer is a multifactorial chronic disease, in which several factors contribute to its pathogenesis and progression. Our immune system is designed to continuously identify and destroy tumor or aberrant cells. However, a compromised immune system has been associated with the development of cancer. In such immune state, cancer cells often develop the ability to hide from the immune surveillance network and adopt intelligent survival tactics which are continuously developing. Therefore, researchers are focusing on boosting anti-tumor immunity by developing novel cancer immunotherapies. Adoptive cell-based cancer therapies are being used, including in vitro expansion and activation of immune eff...

Emerging Concepts in Bacterial Biofilms
  • Language: en
  • Pages: 381

Emerging Concepts in Bacterial Biofilms

The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

Advances in Phytonanotechnology for Treatment of Various Diseases
  • Language: en
  • Pages: 395

Advances in Phytonanotechnology for Treatment of Various Diseases

  • Type: Book
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  • Published: 2023-09-29
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  • Publisher: CRC Press

Several plant bioactives or plant-derived therapeutic molecules have been used against life-threatening diseases and their nanoparticle-mediated delivery greatly improves therapeutic efficacy. Advances in Phytonanotechnology for Treatment of Various Diseases aims to describe past and recent advances achieved in the field of phytonanotechnology. The chapters of this book provide thorough knowledge of medicinal plants, plant bioactives, plant extract-based nanoparticle synthesis, delivery of plant bioactives through nanoparticles, and their therapeutic activity against life-threatening diseases. This book focuses on the therapeutic activity of phytocomponents present in plants from diverse fam...

Innovative Materials for Environmental and Aerospace Applications
  • Language: en
  • Pages: 584

Innovative Materials for Environmental and Aerospace Applications

  • Type: Book
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  • Published: 2024-12-05
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  • Publisher: IGI Global

In settings where environmentally friendly practices and policies are prioritized, sustainability and technological progress thrive, making it essential to study and evaluate innovative approaches. Emerging research in materials science is driving innovative solutions for environmental and aerospace engineering by developing materials that are lighter, stronger, and more sustainable. These advancements not only support greener technologies but also enhance performance, pushing the boundaries of what is possible in aerospace and environmental applications. Innovative Materials for Environmental and Aerospace Applications serves as an inclusive compilation of cutting-edge studies that address important challenges in two connected fields. It explores unique materials and methods that not only strengthen performance but also promote environmental stewardship. Covering topics such as aerospace engineering, hydrogen production, and water purification, this book is an excellent resource for environmental scientists, aerospace professionals, materials scientists, sustainability professionals, academicians, researchers, graduate and postgraduate students, and more.

Cancer Theranostics
  • Language: en
  • Pages: 543

Cancer Theranostics

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging an...

Proceedings of the ... Pakistan Science Conference
  • Language: en
  • Pages: 502

Proceedings of the ... Pakistan Science Conference

  • Type: Book
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  • Published: 1967
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  • Publisher: Unknown

None

Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System
  • Language: en
  • Pages: 128

Sensing the Environment: Regulation of Local and Global Homeostasis by the Skin's Neuroendocrine System

The skin, the body’s largest organ, is strategically located at the interface with the external environment where it detects, integrates and responds to a diverse range of stressors, including solar radiation. It has already been established that the skin is an important peripheral neuroendocrine-immune organ that is closely networked with central regulatory systems. These capabilities contribute to the maintenance of peripheral homeostasis. Specifically, epidermal and dermal cells produce and respond to classical stress neurotransmitters, neuropeptides and hormones, production which is stimulated by ultraviolet radiation (UVR), biological factors (infectious and non-infectious) and other ...

Sustainable Agriculture in the Era of the OMICs Revolution
  • Language: en
  • Pages: 511

Sustainable Agriculture in the Era of the OMICs Revolution

Access to food with enough calories and nutrients is a fundamental right of every human. The global population has exceeded 7.8 billion and is expected to pass 10 billion by 2055. Such rapid population increase presents a great challenge for food supply. More grain production is needed to provide basic calories for humans. Thus, it is crucial to produce 60-110% more food to fill the gap between food production and the demand of future generations. Meanwhile food nutritional values are of increasing interest to accommodate industrialized modern lives. The instability of food production caused by global climate change presents another great challenge. The global warming rate has become more ra...

The Pakistan National Bibliography
  • Language: en
  • Pages: 156

The Pakistan National Bibliography

  • Type: Book
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  • Published: 1989
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  • Publisher: Unknown

None

Pakistan Annual Law Digest
  • Language: en
  • Pages: 866

Pakistan Annual Law Digest

  • Categories: Law
  • Type: Book
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  • Published: 1997
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  • Publisher: Unknown

None