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Protein homeostasis, or “Proteostasis”, lies at the heart of human health and disease. From the folding of single polypeptide chains into functional proteins, to the regulation of intracellular signaling pathways, to the secreted signals that coordinate cells in tissues and throughout the body, the proteostasis network operates to support cell health and physiological fitness. However, cancer cells also hijack the proteostasis network and many of these same processes to sustain the growth and spread of tumors. The chapters in this book are written by world experts in the many facets of the proteostasis network. They describe cutting-edge insights into the structure and function of the ma...
This is a comprehensive and topical history of the Jews in the Soviet Union and is based on firsthand documentary evidence and the application of a pioneering research method into the fate of national minorities. Within a four-part chronological framework, Professor Pinkus examines not only the legal-political status of the Jews, and their reciprocal relationship with the Soviet majority, but also the impact of internal economic, demographic and social processes upon the religious, educational and cultural life of Soviet Jewry. A second layer of analysis describes in depth the complex linkages between the Jews of the Soviet Union, the Jews in other diasporas and the state of Israel itself. The Jews of the Soviet Union marks a major contribution to the historiography and social analysis of its subject and provides a worthy companion to Professor Pinkus's acclaimed documentary study The Soviet Union and the Jews 1948-1967.
This book is the first complete study in English of Antonescu's part in the Second World War. Antonescu was a major ally of Hitler and Romania fielded the third largest Axis army, joined the Tripartite Pact in November 1940 as a sovereign state and participated in the attack on the Soviet Union of 22 June 1941 as an equal partner of Germany.
SILENCED PACES is an elaborated work addressed mainly to people who are willing to enhance their knowledge and understanding about the most troubled times of our world's history. The facts and their sequence are based on historical archives and data. This book is intended to unveil the events buried in the dimness of those times, lived by ordinary peoples, through horrors, sufferings, despair, famine, and unthinkable abuses, during and after the Second World War. The story depicts the shaking period of time between 1930 and 1980, and it's staged in Romania. The events are combined with the "saga" of a family whose daily ordeal solidifies even better the realities of those troubled times. Maybe, this book will help people to better understand the values of life and of their historical heritage, leaving them as a legacy to the coming generations, to be enhanced, shared, and treasured.
This book, The Plot Against the Church, was published prior to the beginning of the Second Vatican Council as a warning of what the dark powers had in store for the Church. The high ranking clerics, writing as Maurice Pinay, stated that the ultimate purpose of the Council was to remove the crime of Deicide from the Jews and assign it instead to the Romans. It is a scholarly work, worthy of consideration of all who would understand Christian history and Christian defense against forces seeking to destroy the Church and Faith. While written in 1962, Rabbi Louis Israel Newman wrote much the same from the Jewish side in his 1925 work Jewish Influence in Christian Reform Movements, which is quoted extensively in The Plot.
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topi
This text explores the evolution of the Jewish question in Romania, from the accession to the throne of the first sovereign of the Hohenzollern dynasty, Carol I, to the emancipation of the Jews after World War I. Social, economic, cultural and political aspects are examined.