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RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.
Biomass, Biofuels and Biochemicals: Advances in Enzyme Technology provides state-of-the-art information on the fundamental aspects and current perspectives in enzyme technology to graduate students, postgraduates and researchers working in industry and academia. The book provides information about the use of enzyme technology as an important tool for biotechnological processes, including food, feed, fuels, textiles, paper, energy and environmental applications. The search for improvements in existing enzyme-catalyzed processes dictates the need to update information on various enzyme technologies. The book gives a snapshot of current practice and research in the area of enzyme technology.
"Taiping Guangji" (太平广记) is the first collection of ancient classical Chinese documentary novels. The book has 500 volumes with 10 catalogues . It is a kind of book based on the documentary stories of the Han Dynasty and the Song Dynasty. 14 people including Li Fang, Hu Mongolian ﹑ Li Mu , Xu Xuan , Wangke Zhen , Song white , Lv Wenzhong worked under Song Taizong Emperor’s command for the compilation. It began in the second year of Taiping Xingguo (977 A.D) and was completed in the following year (978 Ad.). This book is basically a collection of ancient stories compiled by category. The book is divided into 92 categories according to the theme, and is divided into more than 1...
This book aims to introduce the emerging technologies of graphene oxide (GO) in various fields such as industrial, medical, electronics, artificial intelligence, materials-alloys, energy storage devices, optical, physics, mechanical, nanomaterials, and sustainable chemistry. At the current level of development, the properties and binding structure of graphene are important toward the recent applications. The knowledge produced by the graphene oxide could be a much haunting basis for discovering innovative opportunities in the field of emerging trends of research. Future technology expected that the full development will depend only on graphene and its functionalized composite materials. This book highlights the challenges and opportunities associated with GOs. Subject of interest in this book is exploring the opportunities and technologies related to abundant clean energy, pure water, and noble long healthy life.
Selected, peer reviewed papers from the 11th China International Nanoscience and Technology Symposium (CINST 2012), October 21–25, 2012, Kunming, China
A roadmap for easily navigating through the complexities of Chinese herbal medicine, Chinese Herbal Medicine: Modern Applications of Traditional Formulas presents information about herbal formulas in a practical and easy-to-access format. Bridging the gap between classroom study and the clinical setting, the book supplies information on disease sym