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Peripheral Membrane Proteins
The peripheral membrane proteins transduce the extracellular signaling into the cells. The peripheral membrane proteins include the G protein-coupled receptors, receptor tyrosine kinases, channels and transporters. The signals, which are transduced via the peripheral membrane proteins, activate several pathways including G protein signaling, MAPK signaling, TNF signaling, TGF? signaling, Wnt signaling and Hedgehog signaling. The peripheral membrane proteins transduce the signaling from the extracellular ligands into the cells. This book intends to provide a comprehensive overview of the features and signaling of peripheral membrane proteins, which includes the molecular structure and interaction. The insights into membrane proteins associated with diseases and therapeutics and the effects of drugs and chemicals are also discussed in this book.
Cancer Stem Cell Markers and Related Network Pathways
This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
Case Reports in Gastrointestinal Cancers : 2022
This Research Topic aims to collect all the Case Reports submitted to the Gastrointestinal Cancers sections. All the Case Reports submitted to this collection will be personally assessed by a senior Associate Editor before the beginning of the peer-review process. Please make sure your article adheres to the following guidelines before submitting it.
Latest Research into Quality Control
Quality control has an emerging importance in every field of life. Quality control is a process that is used to guarantee a certain level of quality in a product or service. It might include whatever actions a business deems necessary to provide for the control and verification of certain characteristics of a product or service. With the improvement of technology everyday we meet new and complicated devices and methods in different fields. Quality control should be performed in all of those new techniques. In this book "Latest Research Into Quality Control" our aim was to collect information about quality control in many different fields. The aim of this book is to share useful and practical knowledge about quality control in several fields with the people who want to improve their knowledge.
Wide Spectra of Quality Control
Quality control is a standard which certainly has become a style of living. With the improvement of technology every day, we meet new and complicated devices and methods in different fields. Quality control explains the directed use of testing to measure the achievement of a specific standard. It is the process, procedures and authority used to accept or reject all components, drug product containers, closures, in-process materials, packaging material, labeling and drug products, and the authority to review production records to assure that no errors have occurred.The quality which is supposed to be achieved is not a concept which can be controlled by easy, numerical or other means, but it is the control over the intrinsic quality of a test facility and its studies. The aim of this book is to share useful and practical knowledge about quality control in several fields with the people who want to improve their knowledge.
Biomedical Image or Genomic Data Characterization and Radiogenomic/Image-omics
Much of the emphasis in discussions about personalized medicine has been focused on the molecular characterization of tissue samples using microarray technology. However, as genetic differ between and within tumors and are quite heterogeneous, these techniques are limited. Imaging is noninvasive and is often used in routine clinical practice for disease diagnosis, treatment, and prognosis. Imaging is useful to guide disease therapy by providing a more comprehensive view of the entire lesion and it can be used on an ongoing basis to monitor lesion growth and progression or its response to treatment. The imaging includes but not limited to ultrasound, X-ray, computed tomography (CT), magnetic ...
Regulators of G Protein Signaling, Part B
Regulators of G Protein Signaling, Part B continues the in-depth treatment of the topic and covers the RSG protein superfamily including RZ, R4, R7, R12, RhoGEF, and GRK, as well as other heterotrimeric G-protein signaling regulators. - Table of Contents - RZ Subfamily - R4 Subfamily - R7 Subfamily - R12 Subfamily - RhoGEF Subfamily - GRK Subfamily - Other RGS proteins - Activators - Inhibitors - Other Modulators
Metabolic Modulation of Cellular Function
Metabolic pathways and their metabolites are gaining recognition as both sensitive biomarkers for pathological conditions and key modulators of cell fate. In the past, metabolic changes were considered a consequence of gene expression, metabolite control, or environmental changes such as starvation. However, extensive research in the last decade has demonstrated that metabolic changes respond to and influence cellular signaling. This crosstalk between metabolism and cellular signaling is mainly enabled by novel metabolite-mediated modulation of enzymatic activity of rate-limiting steps and post-translational and epigenetic modifications, for which metabolites serve as substrates.
