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This book explores the emerging link between hormones, hormone imbalance and allergies. Beginning with an overview and the genetics of allergy this text looks at the common manifestations and reaction caused by allergies, their pathophysiology and diagnosis before moving to a discussion of the availability and efficacy of therapeutic options including SLIT therapy (Sublingual Immunotherapy).
This book explores the emerging link between hormones, hormone imbalance and allergies. Beginning with an overview and the genetics of allergy this text looks at the common manifestations and reaction caused by allergies, their pathophysiology and diagnosis before moving to a discussion of the availability and efficacy of therapeutic options including SLIT therapy (Sublingual Immunotherapy).
In light of the critical contributions of macrophages and dendritic cells to diverse inflammatory diseases and to immunity and host defense, state-of-the-art approaches to the investigation of their behavior are essential. In Macrophages and Dendritic Cells: Methods and Protocols, expert researchers contribute laboratory protocols involving these two vital cell types functioning at the junction of the innate and acquired immune systems. The volume delves first into isolation and cell culturing then continues with topics such as phagocytosis, genetic manipulation, macrophage activation, and lipid signaling. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Macrophages and Dendritic Cells: Methods and Protocols provides a timely and useful guide for both seasoned investigators and neophytes pursuing this imperative field of study.
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
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The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed
Mumbai is an ever-evolving city, bustling and brimming, never sleeping for a wink. But the past four decades brought upheavals of great magnitude that shaped the city as we know today. Marred by communal riots, gang wars and terrorism, the spirit of Mumbai has emerged indomitable every single time. Born and raised in the lanes of Bombay 3, this is the story of Jagan Kumar who dreams of being a television journalist and changing the world. But once he achieves this, he realises that television journalism has lost its path, now afflicted with sensationalism, corruption and bias. As a crime reporter, he comes across various unscrupulous means that law enforcement agencies adopt to combat organi...